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A.L.Selmi; R.R.Faleiros; J.N.B.M.Andrade; J.L.O.Costa; P.S.P.Santos; N.Nunes, FCAVJ/UNESP

Objective: To determine cardiopulmonary effects of desflurane administration in hypovolemic dogs.

Design: Five healthy, adult dogs were anesthetized with desflurane after a MAP of 60 mmHg was reached following blood withdrawal.

Procedure: Desflurane was delivered by face mask until endotracheal intubation could be performed. Cardiopulmonary effects were determined at 0 (M0), 5 (M1), 15 (M2), 30 (M3), 45 (M4) and 60 (M5) minutes after blood withdrawal. Data were analyzed by ANOVA for repeated measures followed by Tukey�s test.

Results: DAP and MAP decreased after induction until M4. SAP, CO, CI, SV and SVR were not affected. CVP decreased after hypovolemia and was not affected by desflurane. At M0, pH, PaO2, o HCO3-, Ht and Hb were below lower limit values, whilst RR and tidal volume were above normal. Both PaCO2, SaO2 increased during desflurane anesthesia, Na+ was within normal values and K+ slightly below normal. Both Ht and Hb were below normal values and decreased during desflurane anesthesia; pH and K+ were lower at induction reaching normal values at M2.

Conclusions: Desflurane did not alter respiratory function or acid-base values. However, when administered to hypovolemic dogs, it induced significant changes in blood pressure, with minimal effects on cardiac function.

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Alternative Medicine
Animal Welfare
Clinical Pathology
Dental Congress 1:1
Dental Congress 1:2
Dental Congress 1:3
Dental Congress 2:1
Dental Congress 2:2
Dental Congress 2:3
Emergency & Critical Care
Feline Endocrine & Infectious Dz
Feline Gastroenterology
Feline Urology/Nephrology
Infectious & Zoonotic Diseases
Respiratory Medicine
Surgery & Sports Medicine
Oral Presentations
Morbidity Factors Of Anxiety Disorders
PTT Excision Of Ear Canal Polyps
Rabies Antibody Tests: IHA vs Elisa
Hip Luxation: Surgical Repair
Surgical Repair Of Mitral Regurg.
Dental Pulp/Dentin Deposition
Ehrlichiosis Study, Azarbaijans
B. Thuring. Effects On Trichostrongylus
Growth Plate Closure Times, Kangal
Revolution, Dog/Cat Flea Control
Electrical Stim. For Nerve Injuries
BAPN-F For Gastroc. Tendon Healing
Patch Test, Dogs; Human Allergy Stats.
Abd. Adhesion Prevention, Omenectomy
Leptospirosis Study, Tehran
Ehrlichiosis, Protein Alterations
Xenograft For Femural Fx. Repair
Omentum For Tendon Healing
Pet Behavior During Bombing
Evaluation Of Silk Suture
Canine Testis Gene Expression
Radiologic Signs, Spirocerca
Feline Interferon In FeLV/FIV Cats
HbA1c In Diabetic Dogs
Bovine Xenograft For Tibial Repair
Tibial Segmental Defect, Treatment
Bovine Bone Pin For Fracture Repair
Rabies Immunity, Tehran, Dogs
Oral Antibiotics, Owner Compliance
Excision Arthroplasty, Dogs/Cats
Ovine Xenograft For Radial Fractures
Endochondral Ossification
Intertrochanteric Osteotomy Fixation
Immunoglobuline, Atopic Dermatitis
Subclinical Dermatophytosis
Probiotic Strains
Efficacy of Revolution (selamectin)
Bordetella Bronchiseptica
Bone Cement and Graft
Femoral Head
Bacterial Infections, Urinary
Mammary Neoplasias
Bilateral Anterior Hemimelia
Adenocarcinoma, Apocrine Glands
Bone Marrow Toxicity
Carmustine, Lymphoma
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Nutrition, Hyperlipidaemia
Perianal Fistula
L-Carnitine Supplementation
Poster Presentations