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Imaging Findings in Myeloma
Dr. Paul Mellor, DECVIM

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Fig. 1: Abdominal radiograph of a cat with liver enlargement due to myeloma.
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Fig. 2a: Abdominal radiograph of a cat with splenic enlargement due to myeloma (Severine Tasker, University of Bristol).
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Fig. 2b: Ultrasonographic image of splenic enlargement due to myeloma in the same cat as in 2a (Severine Tasker, University of Bristol).
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Fig. 3a: Lateral radiograph of a cat's skull displaying occipital crest osteolysis due to a myeloma related disorder.
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Fig. 3b: Detail of the skull osteolysis from the same cat as in 3a.
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Fig. 4a: Survey lateral spinal radiograph of a case of solitary plasmacytoma of bone. There is marked sclerosis of the lumber vertebra L6 body. This is attributable to palisading new bone formation, most notable at the ventral and lateral margins of the L6 body. Mild to moderate osteolysis is also evident in these locations. The ventral margin of the vertebral canal appears indented due to new bone formation. The vertebral end plates appear unremarkable (Case 1, (Mellor et al 2007b)) (copyright Journal of Feline Medicine and Surgery).
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Fig. 4b: Ventro-dorsal spinal radiograph of a case of solitary plasmacytoma of bone (same case shown in 4a).
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Fig. 5: Survey lateral spinal radiograph of a case of solitary plasmacytoma of bone. The sacral silhouette appears poorly defined, with the cranial sacral end plate most clearly evident. The sacrum is virtually ablated by osteolysis, and surrounded by extensive "wispy" new bone formation that is seen superimposed over the sacroiliac joint and extending into the soft tissue dorsal to the wings of the ilia and caudally into the pelvis to the level of the acetabulae. There is dorsal displacement of the tail. The first coccygeal vertebra appears unaffected. Smooth bridging spondylosis is observed from L6 to S1. The contours of the ilia appear unremarkable. (Case 2 (Mellor et al 2007b)) (copyright Journal of Feline Medicine and Surgery, Elsevier).

Table of Contents
The Veterinary Myeloma Website
Dr. Paul Mellor, DECVIM
Introduction
What are myeloma related disorders
Clinical signs
Diagnosis
Imaging Findings
Clinico-pathological Findings
Anatomical Pathology
Cytology, Histopathology
Other Images
Immunohistochemistry
Mis-diagnosis of MRD
Treatment and Survival
Clinical Research & Trials
MRD References
History, Acknowledgements, Links
Bio

Date Published: June 6, 2007 Paul Mellor


Address (URL): https://www.vin.com/Projects/Myeloma/M07770.htm

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