July 27, 2012

To characterize chronic hepatitis in the Standard Poodle using clinical, laboratory and histopathologic findings.
Dr Bradley
is looking for Standard Poodles with chronic hepatitis. See the trial page for specific information on eligibility.

October 1, 2014

ACI is currently enrolling cases in a nationwide clinical trial to evaluate a monoclonal antibody (AT-005) that is conditionally licensed by the USDA to aid in the treatment of dogs with lymphoma. The study is designed to assess the benefit of adding AT-005 to a multi-agent chemotherapy protocol for dogs with intermediate to high grade T-cell lymphoma.
Dr Johannes
is looking for dogs with T-cell lymphoma. See the trial page for specific information on eligibility.

October 17, 2014

ACI is currently enrolling cases in a nationwide clinical trial to evaluate a monoclonal antibody (AT-005) that is conditionally licensed by the USDA to aid in the treatment of dogs with lymphoma. The study is designed to assess the benefit of adding a T-cell-specific monoclonal antibody to a single agent CCNU chemotherapy protocol for dogs with intermediate to high grade T-cell lymphoma.
Dr Johannes is looking for dogs with T-cell lymphoma. See the trial page for information on eligibility

May 16, 2016

We hope to establish baseline (pre-treatment) levels of activated T-cell expression of IL-2 and IFN-gamma in dogs with anal furunculosis. These baseline values will help us to interpret results using the same assay from dogs with anal furunculosis that are receiving cyclosporine.
Dr Mackin is looking for dogs with anal furunculosis.
See the trial page for specific information on eligibility.

November 1, 2011

The goal of the work is to determine a safe and effective dose of recombinant Listeria monocytogenes that induces Her-2/neu specific T cell immune responses in dogs with appendicular OSA. In addition we hope to determine whether this vaccine can prolong disease free interval and overall survival in dogs with Her-2/neu expressing OSA.
Dr Mason
is looking for dogs with osteosarcoma. See the trial page for specific information on eligibility.

January 17, 2012

Our goal is to be able to identify the genetic cause of the PDA in Corgis in order to improve the health of the breed and also to further our understanding of human PDAs.
Dr Freeman
Dr Freeman

November 1, 2011

This study hopes to find a safe, biologically effective dose of NBD peptide that inhibits constitutive NF-kappaB activity in the malignant B cells of dogs with diffuse large B cell lymphoma.
Dr Mason
is looking for dogs with lymphoma. See the trial page for specific information on eligibility.

January 25, 2007

August 31, 2000

Cat litter additive and diabetesSusan McDonough, VMD Cats with diabetes needed.

June 18, 2010

We hope to find non-invasive markers of feline enteric disease.
Dr Craven
is looking for cats with IBD or intestinal lymphoma. See the trial page for specific information on eligibility.

March 10, 2004

Chronic canine and feline diarrhea
Puppies and kittens that have chronic diarrhea and that have had an initial medical work-up to rule out identifiable causes of chronic diarrhea will be eligible to enroll.
Puppies or Kittens with chronic diarrhea needed.

January 25, 2007

October 10, 2006

The purpose of this study is to determine whether Plavix (clopidogrel) decreases recurrence of thromboembolism in cats compared to aspirin.
Dr. Dan Hogan
is looking for cats with documented evidence of thromboembolism that have survived at least 1 month beyond the acute event.

December 2, 2004

February 12, 2008

April 9, 2007

August 2, 2008

This study aims to determine whether or not orally administered docetaxel is an effective chemotherapy treatment for cats with various carcinomas, with an emphasis on oral squamous cell carcinoma.
Dr Margaret McEntee
is looking for cats with various carcinomas, focusing on oral carcinoma. See the trial page for specific information on eligibility.

August 13, 2007

August 11, 2006

November 1, 2007

August 24, 2000

Serological Investigation of Cuterebra Larval Migration as a Cause of Neurologic Disease in Cats.Andrew Mackin, Mississippi State University Serum samples and larvae needed from cats with Cuterebra myiasis.

June 9, 2006

June 21, 2004

July 6, 2004

August 28, 2002

January 25, 2007

August 5, 2002

July 28, 2015

We are offering Dal and quantitative DEA 1 typing and crossmatching to detect post-transfusion alloantibodies and potentially compatible donors.
Dr Giger is looking for dogs that have had blood transfusions. See the trial page for specific information on eligibility.

August 6, 2007

December 2, 2004

September 25, 2008

Hair coat disorders in Schipperkes have not been extensively characterized. To further investigate Alopecia X in plush-coated breeds, six healthy, unaffected Schipperke dogs and 12 Schipperke dogs with a history of symmetrical non-inflammatory alopecia will be entered into the study to determine if the condition in the Schipperke is similar to that in other breeds.
Dr May
is looking for Schipperkes with alopecia. See the trial page for specific information on eligibility.

September 4, 2002

March 10, 2004

Chronic canine and feline diarrhea
Puppies and kittens that have chronic diarrhea and that have had an initial medical work-up to rule out identifiable causes of chronic diarrhea will be eligible to enroll.
Puppies or Kittens with chronic diarrhea needed.

August 18, 2003

January 25, 2007

January 25, 2007

February 4, 2009

November 6, 2006

This study hopes to find genes that increase the risk for diabetes mellitus in Samoyed and Australian Terrier dogs. Early genetic identification of carriers and dogs that are likely to develop diabetes may allow for decreasing the incidence of this disease in dogs.
Dr Rebecka Hess
is looking for Samoyeds and Australian Terriers with Diabetes Mellitus. Samoyeds or Australian Terriers without Diabetes Mellitus are also needed as controls. See the trial page for specific infor

January 24, 2008

November 6, 2006

November 6, 2006

January 29, 2007

The study hopes to identify genes that may be associated with histiocytic ulcerative colitis in Boxer dogs, in order to enable effective screening and eradication of HUC.
Dr Simpson
is looking for Boxers that have been definitively diagnosed in the past with HUC (GCB) and Boxers that have been free of HUC throughout their lives. DNA samples are required - see Trial page for full details.

September 19, 2008

We hope to determine if superselective intra-arterial administration of chemotherapy and NSAIDs to urothelial tumors results in improved tumor response rates.
Dr Chick Weisse
is looking for dogs with transitional cell carcinoma. See the trial page for specific information on eligibility.

June 30, 2014

Investigating the Genetic Basis of Hypoadrenocorticism in Standard Poodles
We hope to move towards finding the genetic defect in Standard Poodles with typical hypoadrenocorticism

April 25, 2008

December 20, 2002

January 30, 2008

October 18, 2004

July 24, 2007

April 12, 2016

This trial is evaluating whether T lymphocytes, genetically modified to express a chimeric antigen receptor against CD20, can be administered safely to dogs with relapsed B cell lymphoma and whether they can eliminate B cells and prolong overall survival.
Dr Mason is looking for dogs with B-cell lymphoma have relapsed after initial remission.
See the trial page for specific information on eligibility.

February 26, 2007

January 19, 2009

We are investigating the etiopathogenesis of Protein-Losing Enteropathy (PLE) or Yorkshire Terriers, with particular focus on the development of intestinal crypt lesions, and their role in contributing to enteric protein loss. Since the Yorkshire Terrier is an at-risk breed for development of PLE, we also aim to explore the possibility of a genetic basis to the disease.
Dr Simpson
is looking for Yorkshire Terriers with Protein-losing enteropathy. See the trial page for specif

September 4, 2002

September 29, 2009

Lymphoma is a readily treatable disease in dogs, with reasonable remission times when using more advanced protocols. SP19 is a modification of the UWM protocol that is less management-intensive.
Dr Rosenthal
is looking for dogs with Lymphoma. See the trial page for specific information on eligibility.

July 21, 2011

We want to determine whether drug-specific T cells can be found in dogs with sulfonamide drug hypersensitivity, and what molecules they target. These results will help us to understand pathogenesis and may help generate prevention strategies.
Dr Trepanier
is looking for dogs with sulfonamide hypersensitivity. See the trial page for specific information on eligibility.

June 25, 2008

July 16, 2008

June 9, 2006

August 28, 2002

January 30, 2008

March 3, 2010

The purpose of this study is to perform a proteomic comparison of the plasma protein profiles of cats with neoplastic and inflammatory pancreatic diseases to identify differences in protein expression. Such proteins may serve in the future as biomarkers for pancreatic neoplasia.
Dr Meachem
is looking for cats with pancreatic neoplasia or pancreatitis. See the trial page for specific information on eligibility.

April 9, 2008

October 1, 2010

September 19, 2008

January 30, 2008

August 31, 2006

August 28, 2006

December 5, 2006

November 24, 2003

July 13, 2009

April 24, 2012

November 19, 2003

February 4, 2009

Our long term research goal is to optimize pacing techniques for companion animals requiring pacemaker therapy. Such evaluation is justified as complete heart block is a common debilitating condition treated by veterinary cardiologists.
Dr Estrada
is looking for dogs with 3rd degree AV Block. See the trial page for specific information on eligibility.

October 10, 2008

April 9, 2008

August 16, 2012

We hope to improve the diagnosis and monitoring of dogs with IMHA by using several methods. We hope this will lead to a better and standardized diagnostic scheme to diagnose IMHA in dogs
Dr Giger
is looking for dogs with IMHA. The investigators are offering free diagnostic testing on IMHA cases for a limited time See the trial page for specific information on eligibility.

July 16, 2008

August 6, 2007

January 28, 2005

October 15, 2001

September 18, 2008

This study aims to determine whether adjunctive medical therapy with polyethylene glycol or methylprednisolone sodium succinate improves the outcome of surgically treated dogs with disc herniations more than placebo.
Dr Olby
is looking for dogs with acute thoracolumbar disc herniation that can be taken to one of the participating centers for the study. See the trial page for specific information on eligibility.

September 25, 2008

The purpose of this study is to determine if dogs with acquired myasthenia gravis have similar genes (MHC haplotype). We will use DNA collected from blood cells or from cells from the lining of the mouth to do the genetic analysis. The genetic analysis will be done in the Veterinary School at UC Davis.
Dr Vernau
is looking for dogs with acquired myasthenia gravis. See the trial page for specific information on eligibility.

October 10, 2007

This prospective study will compare a new minimally invasive technique to a historical surgical control for the fixation for intramural ureteral ectopia, to identify differences in post-operative continence rates, level of post-operative urinary infections and parameters of pain in the first week post-intervention. In doing so we hope to determine whether there is a therapeutic advantage to this technique or if there is a significant decrease in post-operative pain.
Dr Berent