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DEMONSTRATION OF THE EFFICACY OF REVOLUTION® FOR THE CONTROL AND TREATMENT OF SARCOPTIC MANGE (S. scabiei) IN DOGS, EAR MITES (O. cynotis) IN DOGS AND CATS AND THE TREATMENT OF INTESTINAL HOOKWORMS (A. tubaeforme) AND ASCARIDS (T. cati) IN CATS.

H.A. Weinberg, A.L. Trettien, S.E. Simms

The efficacy of Revolution® (selamectin) against S. scabiei, O. cynotis, A. tubaeforme and T. cati was evaluated in a multi-center study employing 75 veterinary clinics and 197 households. A total of 473 dogs and cats were enrolled.

Diagnosis of mite infestation was based on the microscopic presence of mites in either skin scrapings or aural debris. A fecal centrifugation-flotation method was used to detect fecal ova. Six mg/kg of Revolution was applied on day 0 and if needed, day 30.

Percentage reductions for viable S. scabiei infestation for RevolutionÒ treatments on days 30 and 60 versus day 0 were 96.8% and 100% respectively. Percentage reductions for O. cynotis were 90.3% on day 30 and 98.6% on day 60. Percentage reductions in geometric mean A. tubaeforme egg counts were 98.3% and 100% on days 30 and 60 respectively. Percentage reductions in geometric mean T. cati egg counts were 95.1% and 100% on days 30 and 60 respectively.

RevolutionÒ administered topically at monthly intervals as a unit dose providing the recommended minimum of 6 mg/kg is safe and effective against natural infestation of sarcoptic mange in dogs, ear mites in dogs and cats and intestinal hookworms and roundworms in cats.

Signature: _____________________________ Date: ________________

Henry Weinberg, D.V.M


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