Vet Clinical Trials
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Dogs
System
Gastrointestinal
Identification of Genetic Risk in Shetland Sheepdogs with Gallbladder Mucocele Formation
Risk Factors for Nutritionally-mediated DCM in Healthy Dogs of 2 Size Groups: The Role of Diet Category, Taurine, Cardiac Biomarkers, and Metabolomics
Developmental
Genetic Mapping of Legg Calve Perthes Disease
Digestive
Granulomatous Disease
EHBDO in dogs and cats
Endocrine
Incidence, Prevalence, and Genetics of Canine Diabetes
Musculoskeletal
Genetic Mapping of Legg Calve Perthes Disease
Legg-Calve-Perthes Disease
Hypertrophic Osteodystrophy (HOD)
The Use of a Minimally Invasive Integrated Endoscopic System to Perform Hemilaminectomies in Chondrodystrophic Dogs with Thoracolumbar Intervertebral Disc Extrusions
Neurological
Epilepsy Research
Spina Bifida
Identification of Genetic Risk in Collies and Shetland Sheepdogs with Epilepsy
The Use of a Minimally Invasive Integrated Endoscopic System to Perform Hemilaminectomies in Chondrodystrophic Dogs with Thoracolumbar Intervertebral Disc Extrusions
Respiratory
Skin
Measurement of IL-31 Levels in Dogs with Cutaneous Epitheliotropic T Cell Lymphoma: Its Association with Pruritus and the use of Lokivetmab (Cytopoint) as an Antipruritic Treatment
Transcriptome Profiling of Canine Familial Dermatomyositis (DMS) Skin Lesions and Treatment in Collies and Shetland sheepdogs
Urinary
Use of Canine Struvite Dissolution Diet in the Management of Infection Induced Struvite Stones in Dogs
Disease
Degenerative
Genetic Mapping of Legg Calve Perthes Disease
Legg-Calve-Perthes Disease
Incidence, Prevalence, and Genetics of Canine Diabetes
Prospective randomized clinical trial of doxepin in canine laryngeal paralysis
Developmental
Spina Bifida
Genetic
Granulomatous Disease
Legg-Calve-Perthes Disease
Spina Bifida
Hypertrophic Osteodystrophy (HOD)
Identification of Genetic Risk in Collies and Shetland Sheepdogs with Epilepsy
Molecular mapping and characterization of the genetic modifier associated with Collie Eye Anomaly (CEA) and Colobomas
Risk Factors for Nutritionally-mediated DCM in Healthy Dogs of 2 Size Groups: The Role of Diet Category, Taurine, Cardiac Biomarkers, and Metabolomics
Inflammatory/Infectious
Granulomatous Disease
Transcriptome Profiling of Canine Familial Dermatomyositis (DMS) Skin Lesions and Treatment in Collies and Shetland sheepdogs
Use of Canine Struvite Dissolution Diet in the Management of Infection Induced Struvite Stones in Dogs
Neoplastic
Canine Mammary Tumors
Contrast Enhanced Imaged Guided Surgery for Cancer
Neoplastic
Measurement of IL-31 Levels in Dogs with Cutaneous Epitheliotropic T Cell Lymphoma: Its Association with Pruritus and the use of Lokivetmab (Cytopoint) as an Antipruritic Treatment
Nutrtition
Use of Canine Struvite Dissolution Diet in the Management of Infection Induced Struvite Stones in Dogs
Toxic
Other
Identification of Genetic Risk in Shetland Sheepdogs with Gallbladder Mucocele Formation
EHBDO in dogs and cats
Miscellaneous
Cannabinoid Therapeutic Drug Monitoring
Cats
System
Cardiovascular
Feline Cardiomyopathy Consortium
Study of the Utility of Rivaroxaban or Clopidogrel for prevention of recurrent Arterial Thromboembolism in cats (SUPERCAT)
Digestive
EHBDO in dogs and cats
Endocrine
Genetic Mapping of Diabetes Mellitus in the Cat
The CATPAD study: Evaluation of markers of pancreatic disease in cats before and after switching to a special diet for kidney disease or diabetes mellitus
Gastrointestinal
The CATPAD study: Evaluation of markers of pancreatic disease in cats before and after switching to a special diet for kidney disease or diabetes mellitus
Disease
Genetic
Genetic Mapping of Diabetes Mellitus in the Cat
Inflammatory/Infectious
Feline Vector-Borne Disease (FVBD) in Cats
Toxic
Other
EHBDO in dogs and cats
Study of the Utility of Rivaroxaban or Clopidogrel for prevention of recurrent Arterial Thromboembolism in cats (SUPERCAT)
Miscellaneous
Cannabinoid Therapeutic Drug Monitoring
Other Animals
Exotic Tumor Database
Grey Parrot Anatomy Project
Outcomes of Surgical Management of Horses Undergoing Ventral Midline Celiotomy for Colic with Abnormalities of the Dorsal Mesenteric Attachments of the Colon and Cecum
Seasonal Pasture Myopathy in Horses
Closed Trials
Closed
Cats
Active, Not Recruiting
Dogs
Chronic Hepatitis in Standard Poodles (Study Closed)
Conditionally Licensed Monoclonal Antibody + Multi-agent Chemotherapy for Dogs with T-Cell Lymphoma (Study Closed)
Conditionally Licensed Monoclonal Antibody + CCNU Chemotherapy for Dogs with T-Cell Lymphoma (Study Closed)
Effects of Cyclosoprine on Activated T Cell Expression of IL-2 and IFN-gamma in Dogs (Study Closed)
Evaluation of Listeria monocytogenes (Study Closed)
Genetic Cause of Patent Ductus Arteriosus (PDA) in Pembroke Welsh Corgis (Study Closed)
NBD peptide as an adjunct therapy for the treatment of canine diffuse large B cell lymphoma (Study Closed)
Complete
Cats
Calcium Oxalate Urolithiasis (Study Closed)
Diabetes, cat litter (Trial Ended)
Feline Enteropathies (Study Closed)
Diarrhea (Study Closed)
Evaluation of Calcium Metabolism (Study Closed)
FATCAT (Study Closed)
Squamous Cell Carcinoma (Rimadyl®)
Myeloma-related Disorders
Bite Wound Retroviral Prevalence
Docetaxel for Carcinomas (Study Closed)
Prosaptide
(TM)
TX14(A) (Study Closed)
Idiopathic Hypercalcemia (Study Closed)
Tritrichomonas foetus
Cuterebra (Project Ended)
Transdermal Gel Absorption
Transdermal vs Oral Amitriptyline
Vaccine-associated granulomas
West Nile Virus (Study Ended)
Dogs
Calcium Oxalate Urolithiasis (Study Closed)
Azathioprine (Trial Ended)
Canine Blood Typing and Compatibility of Transfused Dogs (Study Closed)
Intestinal-based probiotic
Transitional Cell Carcinoma
Hair Coat Disorder (Study Closed)
Diarrhea Clinical Study
Diarrhea (Study Closed)
Drug Toxicity
Diet For Bladder Stones (Study Closed)
Struvite Stones
Severe Pulmonic Stenosis (Study Closed)
Diabetes Mellitus (Study Closed)
Cryptorchidism
Ectopic Ureters
Idiopathic Epilepsy
Histiocytic Ulcerative Colitis (Study Closed)
Urothelial Carcinoma (Study Closed)
Hypoadrenocorticism in Standard Poodles (Study Closed)
Vaccine-Associated Reactions
Ivermectin Toxicity (Study Ended)
Hemolytic Anemia
Mitochondrial Disorders
Multiple Myeloma
Pilot study of re-directed autologous T cell therapy for drug resistant or refractory CD20+ B cell lymphoma (Study Closded)
Gabapentin Administration
Protein Losing Enteropathy (Study Closed)
Renal Failure (Study Ended)
RMUW-19 Trial (Study Closed)
Idiosyncratic Sulfonamide Toxicity - Dogs (Study Closed)
Osteochondrosis in Great Dane (Study Closed)
Fecal Sample Testing for Parvovirus
Transdermal Gel Absorption
West Nile Virus (Study Ended)
Complete and Published
Cats
Azodyl in Renal Failure
Pancreatic Neoplasia (Study Closed)
Diabetes Treatment Survey (Study Closed)
Mirtazapine in Cats (Study Closed)
Docetaxel Treatment (Study Closed)
Pituitary Tumors (Study Closed)
Thyroid Gland: Feline
Cytauxzoonosis in Cats (Study Closed)
Squamous Cell Carcinoma(DFMO)
Dogs
Canine Nasal Carcinoma
Canine Thyroid-Aggression (Study Closed)
Certifect-associated Pemphigus Foliaceus-like Reactions
Chylothorax
Heart Block (Study Closed)
Subaortic Stenosis (Study Closed)
Diabetes Treatment Survey (Study Closed)
Diagnosis of IMHA in Dogs (Study Closed)
Doxycycline Therapy
Levetiracetam
Canine Idiopathic Rhinitis
Malignant Hyperthermia
Methylprednisolone and Polyethylene (Study Closed)
Acquired Myasthenia Gravis (Study Closed)
Ureteral Ectopia (Study Closed)
Appendicular Osteosarcoma
Tumor-bearing Canine Antebrachii (Study Closed)
Prospective randomized clinical trial of doxepin in canine laryngeal paralysis
Evolution and Geographic Spread
Renal Failure
MDR-1 genotype in dogs
Appendicular Osteosarcoma (Pain)
Vector-borne Bacteria
Other Animals
Proventriculus:Keel Ratio
Rhodococcus equi/Zithromax
Treatment of Avian Squamous Cell Carcinoma
Vet Clinical Trials
Complete
Cats
Calcium Oxalate Urolithiasis in Dogs (Study Closed)
January 25, 2007
Cat Litter Additive And Diabetes Trial - (Trial Ended)
August 31, 2000
Cat litter additive and diabetesSusan McDonough, VMD Cats with diabetes needed.
Clinical Research on Serum Markers for Feline Enteropathies (Study Closed)
June 18, 2010
We hope to find non-invasive markers of feline enteric disease.
Dr Craven
is looking for cats with IBD or intestinal lymphoma. See the trial page for specific information on eligibility.
Diarrhea in Puppies and Kittens (Study Closed)
March 10, 2004
Chronic canine and feline diarrhea
Puppies and kittens that have chronic diarrhea and that have had an initial medical work-up to rule out identifiable causes of chronic diarrhea will be eligible to enroll.
Puppies or Kittens with chronic diarrhea needed.
Evaluation of Calcium Metabolism and Urinary Saturation in Cats (Study Closed)
January 25, 2007
Feline Aortic Thromboembolism: Clopidogrel vs Aspirin Trial: FATCAT (Study Closed)
October 10, 2006
The purpose of this study is to determine whether Plavix (clopidogrel) decreases recurrence of thromboembolism in cats compared to aspirin.
Dr. Dan Hogan
is looking for cats with documented evidence of thromboembolism that have survived at least 1 month beyond the acute event.
Feline Oral Squamous Cell Carcinoma (Study Closed)
December 2, 2004
Immunophenotyping Feline Myeloma-related Disorders
February 12, 2008
National Feline Abscess/Bite Wound Retroviral Prevalence Study (Study Closed)
April 9, 2007
Phase II Evaluation of Oral Docetaxel in Cats with Carcinomas (Study Closed)
August 2, 2008
This study aims to determine whether or not orally administered docetaxel is an effective chemotherapy treatment for cats with various carcinomas, with an emphasis on oral squamous cell carcinoma.
Dr Margaret McEntee
is looking for cats with various carcinomas, focusing on oral carcinoma. See the trial page for specific information on eligibility.
Prosaptide
(TM)
TX14(A) in Feline Diabetic Neuropathy (Study Closed)
August 13, 2007
Risk Factors for Cats with Idiopathic Hypercalcemia (Study Closed)
August 11, 2006
Role of Feline
Tritrichomonas foetus
in Venereal Infection (Study Closed)
November 1, 2007
Serological Investigation of Cuterebra Larval Migration as a Cause of Neurologic Disease in Cats - (Project Ended)
August 24, 2000
Serological Investigation of Cuterebra Larval Migration as a Cause of Neurologic Disease in Cats.Andrew Mackin, Mississippi State University Serum samples and larvae needed from cats with Cuterebra myiasis.
Transdermal Gel Drug Absorption in Dogs and Cats (Study Closed)
June 9, 2006
Transdermal vs Oral Amitriptyline in Cats (Multiple Dose Testing) (Study Closed)
June 21, 2004
Vaccine-Associated Feline Sarcoma (Study Suspended)
July 6, 2004
West Nile Virus Update - (Study ended)
August 28, 2002
Dogs
Calcium Oxalate Urolithiasis in Dogs (Study Closed)
January 25, 2007
Canine Azathioprine Project - (Trial Ended)
August 5, 2002
Canine Blood Typing and Compatibility of Transfused Dogs (Study Closed)
July 28, 2015
We are offering Dal and quantitative DEA 1 typing and crossmatching to detect post-transfusion alloantibodies and potentially compatible donors.
Dr Giger
is looking for dogs that have had blood transfusions. See the trial page for specific information on eligibility.
Clinical Study of Improved Management of Advanced Kidney Disease in Dogs Using an Intestinal-based probiotic
August 6, 2007
Clinical Trial on Canine Transitional Cell Carcinoma (Study Closed)
December 2, 2004
Description and Characterization of a Hair Coat Disorder in Schipperkes (Study Closed)
September 25, 2008
Hair coat disorders in Schipperkes have not been extensively characterized. To further investigate Alopecia X in plush-coated breeds, six healthy, unaffected Schipperke dogs and 12 Schipperke dogs with a history of symmetrical non-inflammatory alopecia will be entered into the study to determine if the condition in the Schipperke is similar to that in other breeds.
Dr May
is looking for Schipperkes with alopecia. See the trial page for specific information on eligibility.
Diarrhea Clinical Study - (Study Ended)
September 4, 2002
Diarrhea in Puppies and Kittens (Study Closed)
March 10, 2004
Chronic canine and feline diarrhea
Puppies and kittens that have chronic diarrhea and that have had an initial medical work-up to rule out identifiable causes of chronic diarrhea will be eligible to enroll.
Puppies or Kittens with chronic diarrhea needed.
Drug Toxicity (Study Closed)
August 18, 2003
Evaluation of a new diet for managing Dalmatians that have had urate bladder stones (Study Closed)
January 25, 2007
Evaluation of an alternative method for dissolving infection-induced struvite stones in dogs (Study Closed)
January 25, 2007
Evaluation of Fatty Acid Supplementation in Dogs with Severe Pulmonic Stenosis (Study Closed)
February 4, 2009
Genetic markers for Diabetes Mellitus in Samoyed and Australian Terrier dogs (Study Closed)
November 6, 2006
This study hopes to find genes that increase the risk for diabetes mellitus in Samoyed and Australian Terrier dogs. Early genetic identification of carriers and dogs that are likely to develop diabetes may allow for decreasing the incidence of this disease in dogs.
Dr Rebecka Hess
is looking for Samoyeds and Australian Terriers with Diabetes Mellitus. Samoyeds or Australian Terriers without Diabetes Mellitus are also needed as controls. See the trial page for specific infor
Genetics of Cryptorchidism in Siberian Huskies (Study Closed)
January 24, 2008
Genetics of Ectopic Ureters in Newfoundland Dogs (Study Closed)
November 6, 2006
Genetics of Idiopathic Epilepsy in Border Collie Dogs (Study Closed)
November 6, 2006
Identification of genes associated with histiocytic ulcerative colitis (granulomatous colitis of Boxers) (Study Closed)
January 29, 2007
The study hopes to identify genes that may be associated with histiocytic ulcerative colitis in Boxer dogs, in order to enable effective screening and eradication of HUC.
Dr Simpson
is looking for Boxers that have been definitively diagnosed in the past with HUC (GCB) and Boxers that have been free of HUC throughout their lives. DNA samples are required - see Trial page for full details.
Intra-Arterial Chemotherapy for Non-Resectable Canine Urothelial Carcinoma (Study Closed)
September 19, 2008
We hope to determine if superselective intra-arterial administration of chemotherapy and NSAIDs to urothelial tumors results in improved tumor response rates.
Dr Chick Weisse
is looking for dogs with transitional cell carcinoma. See the trial page for specific information on eligibility.
Investigating the Genetic Basis of Hypoadrenocorticism in Standard Poodles (Study Closed)
June 30, 2014
Investigating the Genetic Basis of Hypoadrenocorticism in Standard Poodles
We hope to move towards finding the genetic defect in Standard Poodles with typical hypoadrenocorticism
Investigation of Antigenic Causes of Vaccine-Associated Allergic Reactions in Dogs (Study Closed)
April 25, 2008
Ivermectin Toxicity - (Study Ended)
December 20, 2002
Liposomal Clodronate as a Novel Treatment for Imune-Mediated Hemolytic Anemia in Dogs (Study Closed)
January 30, 2008
Mitochondrial Disorders (Study Closed)
October 18, 2004
Novel Chemotherapy for Canine Multiple Myeloma (Study Closed)
July 24, 2007
Pilot study of re-directed autologous T cell therapy for drug resistant or refractory CD20+ B cell lymphoma (Study Closded)
April 12, 2016
This trial is evaluating whether T lymphocytes, genetically modified to express a chimeric antigen receptor against CD20, can be administered safely to dogs with relapsed B cell lymphoma and whether they can eliminate B cells and prolong overall survival.
Dr Mason is looking for dogs with B-cell lymphoma have relapsed after initial remission.
See the trial page for specific information on eligibility.
Preemptive Gabapentin Administration
February 26, 2007
Protein Losing Enteropathy in Yorkshire Terriers (Study Closed)
January 19, 2009
We are investigating the etiopathogenesis of Protein-Losing Enteropathy (PLE) or Yorkshire Terriers, with particular focus on the development of intestinal crypt lesions, and their role in contributing to enteric protein loss. Since the Yorkshire Terrier is an at-risk breed for development of PLE, we also aim to explore the possibility of a genetic basis to the disease.
Dr Simpson
is looking for Yorkshire Terriers with Protein-losing enteropathy. See the trial page for specif
Renal Failure, Canine - (Study Ended)
September 4, 2002
RMUW-19 Trial (Study Closed)
September 29, 2009
Lymphoma is a readily treatable disease in dogs, with reasonable remission times when using more advanced protocols. SP19 is a modification of the UWM protocol that is less management-intensive.
Dr Rosenthal
is looking for dogs with Lymphoma. See the trial page for specific information on eligibility.
Role of Drug-Specific T Cells in Idiosyncratic Sulfonamide Toxicity in Dogs (Study Closed)
July 21, 2011
We want to determine whether drug-specific T cells can be found in dogs with sulfonamide drug hypersensitivity, and what molecules they target. These results will help us to understand pathogenesis and may help generate prevention strategies.
Dr Trepanier
is looking for dogs with sulfonamide hypersensitivity. See the trial page for specific information on eligibility.
Study of the Genetics of Osteochondrosis in the Great Dane (Study Closed)
June 25, 2008
Testing of Canine Fecal Samples for the Presence of Parvovirus using Real-time PCR, and Genetic Characterization of the Isolates (Study Closed)
July 16, 2008
Transdermal Gel Drug Absorption in Dogs and Cats (Study Closed)
June 9, 2006
West Nile Virus Update - (Study ended)
August 28, 2002
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