Introduction

Granulosa cell tumor is a primary ovarian neoplasia in the dogs which normally occurs in elderly bitches with a median age of 12 years old.

Objectives

This study aims to present the discovery of granulosa cell tumor and ovarian cyst in young dog that have not been reported yet.

Methods

A 3-year-old, female Yorkshire terrier was referred to Theriogenology Center at the Kasetsart University Veterinary Teaching Hospital, Bangkok, Thailand with clinical signs of vulva swelling for 2 years, since she had her first estrus until present time, and sign of abnormal frequent estrus every 2–3 months. Complete blood count examination, vaginal cytology and ultrasonography were performed. However, client denied to measure levels of serum sex hormones.

Results

The results showed normal blood parameters from complete blood count. Vaginal cytology showed about 20% cornification of vaginal epithelial cells, which indicated the influence of estrogen. Endometrial hyperplasia and cystic lesion on right ovary were found on ultrasonographic images. The dog was diagnosed with ovarian cyst on right ovary. Surgical correction was performed by ovariohysterectomy.

For further diagnosis, ovarian tissues from both ovaries were collected and submitted for biopsy. The histopathological results revealed that the dog had non-functional ovarian cyst, cystic subsurface epithelial structure on the right ovary, and granulosa cell tumor with the presence of monolayered clusters of cells and acinar to tubular pattern on the left ovary.

Conclusions

This is the case demonstrating the discovery of granulosa cell tumor and ovarian cyst in young dog, which is quite a rare case.