December 4, 2023

The long term goal of this research is to determine which gene(s) are responsible for predisposition of Shetland sheepdogs to mucocele formation. This will enable a better understanding of pathogenesis of mucocele formation in this breed.
Dr. Gookin is looking for Shetland Sheepdogs with gallbladder mucocele. See the trial page for specific information on eligibility.

February 19, 2024

We hope to identify differences in cardiac parameters related to diet and/or breed size, and to investigate underlying factors that may be related to those differences.
Drs Larsen and Stern are looking for dogs fed “grain free” diets.

August 4, 2015

Legg Calve Perthes Disease (avascular necrosis of the femoral head) affects dogs. A genetic basis is suspected.
Dr Todhunter is looking for dogs with Legg Calve Perthes Disease.
See the trial page for specific information on eligibility.

January 7, 2015

Search For A Dog With X-Linked Chronic Granulomatous Disease
Drs. Harry Malech and Sebastian Brenner
Examples of canine patients that may be of value to them are young Weimaraners with recurrent infection secondary to suspected neutrophil dysfunction, or young dogs from other breeds with a history of chronic recurring infections, particularly with organisms such as Aspergillus, Staphylococcus, Serratia or Burkholderia cepacia.

January 14, 2015

This FULLY FUNDED study evaluates the treatment for extra hepatic biliary duct obstruction (EHBDO) in dogs and cats using endoscopy and retrograde stenting to improve the morbidity and mortality.
Dr Berent is looking for dogs and cats with biliary obstructions. See the trial page for specific information on eligibility.

May 15, 2017

The survey hopes to use this data to investigate the prevalence, incidence, and potentially mode of inheritance of diabetes mellitus in dogs at increased risk for the disease, as well as that of the general population and those at decreased risk.
Dr Cai is looking for dogs with and without diabetes mellitus.
See the trial page for specific information on eligibility.

August 4, 2015

Legg Calve Perthes Disease (avascular necrosis of the femoral head) affects dogs. A genetic basis is suspected.
Dr Todhunter is looking for dogs with Legg Calve Perthes Disease.
See the trial page for specific information on eligibility.

November 3, 2008

Legg-Calve-Perthes Disease (LCPD) is a developmental disorder affecting the hip joint of small-breed puppies. Our study aims to identify (1) the mode of inheritance of LCPD in several small breeds and (2) candidate genes that may either cause the disease or be involved in the disease process through whole-genome association mapping.
Dr Starr
is looking for dogs with Legg-Calve-Perthes disease. See the trial page for specific information on eligibility.

December 31, 2013

This study aims to identify the molecular cause for hypertrophic osteodystrophy. HOD is a familial disorder with an unknown etiology.
Dr Safra
is looking for dogs with hypertrophic osteodystrophy. See the trial page for specific information on eligibility.

December 28, 2020

To evaluate the use of a minimally invasive approach to perform hemilaminectomies in certain dogs with intervertebral disc herniations. A secondary goal is to compare the MIS hemilaminectomy to the standard approach. Where available, the long-term outcome of patients will also be included.
Dr Bartner is looking for chondrodystrophic dogs (e.g. Dachshunds) with acute thoracolumbar disc disease requiring surgery. See the trial page for specific information on eligibility.

October 1, 2002

Canine Epilepsy Research Consortium is studying the genetics of epilepsy in all purebred dogs
To ensure the success of the study Dr. Ned Patterson, DVM from the Canine Genetics Lab, Department of Small Animal Clinical Sciences wants to obtain DNA samples and health information from more families (including siblings, parents, grandparents, offspring or distant relatives) in which one or more members has epilepsy.
Dogs or dogs with a family history of epilepsy are needed.

January 20, 2009

We hope to identify candidate genes associated with canine structural birth defects, specifically spina bifida and cleft lip/palate in the bulldog and other brachycephalic breeds. This would allow us to develop a genetic test that could identify affected dogs and carrier dogs.
Dr Starr
is looking for Bulldogs or brachycephalic dogs with spina bifida or labio-palatine closure defects. See the trial page for specific information on eligibility.

July 20, 2022

Objectives: 1. Conduct a genome-wide association study (GWAS) to identify genomic regions associated with epilepsy in collies and shetland sheepdogs 2. Generate whole genome resequencing data to identify putative causal variants in associated regions.
Dr Clark is looking for Collies and Shetland Sheep dogs with epilepsy. See the trial page for specific information on eligibility.

December 28, 2020

To evaluate the use of a minimally invasive approach to perform hemilaminectomies in certain dogs with intervertebral disc herniations. A secondary goal is to compare the MIS hemilaminectomy to the standard approach. Where available, the long-term outcome of patients will also be included.
Dr Bartner is looking for chondrodystrophic dogs (e.g. Dachshunds) with acute thoracolumbar disc disease requiring surgery. See the trial page for specific information on eligibility.

September 10, 2021

Humans as well as dogs with cutaneous epitheliotropic T cell lymphoma (CETL) often suffer from intense itchiness which can cause significant discomfort and can affect quality of life. Can this itchiness be controlled with Cytopoint?
Dr Souza is looking for dogs with epitheliotropic T-cell Lymphoma. See the trial page for specific information on eligibility.

July 20, 2022

To evaluate the molecular signature of canine familial DMS using RNA sequencing in Collies and Shelties.
Dr Banovic is looking for Collies and Shelties with cutaneous dermatomyositis. See the trial page for specific information on eligibility.

August 30, 2017

We hope to provide another effective dietary option to struvite dissolution in dogs. By feeding the test diet (brand blinded to client) and antibiotics we expect that dissolution of canine struvite bladder stones will occur within a 12-week period.
Dr Westropp is looking for dogs with struvite uroliths.
See the trial page for specific information on eligibility.