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ABSTRACT OF THE WEEK

The Veterinary clinics of North America. Small animal practice
Volume 47 | Issue 1 (January 2017)

Lymphoid Neoplasia: Correlations Between Morphology and Flow Cytometry.

Vet Clin North Am Small Anim Pract. January 2017;47(1):53-70.
Emily D Rout1, Paul R Avery2
1 Department of Microbiology, Immunology, and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, 314-4 Diagnostic Medicine Center, 200 West Lake Street, 1644 Campus Delivery, Fort Collins, CO 80523-1644, USA.; 2 Department of Microbiology, Immunology, and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, 309 Diagnostic Medicine Center, 200 West Lake Street, 1644 Campus Delivery, Fort Collins, CO 80523-1644, USA. Electronic address: paul.avery@colostate.edu.
Copyright © 2016 Elsevier Inc. All rights reserved.

Abstract

Cytology is commonly used to diagnose lymphoma and leukemia. Frequently, a diagnosis of lymphoproliferative disease can be obtained via cytology, and some of the common subtypes of canine lymphoma and leukemia can have characteristic cytologic features. Flow cytometry is a critical tool in the objective diagnosis and further characterization of lymphoma and leukemia. Features of the immunophenotype, such as expression of certain cell surface proteins or cell size, can provide important prognostic information. This review describes the cytologic features, flow cytometry immunophenotype, and immunophenotypic prognostic information for 6 major types of canine lymphoma and leukemia.

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Archives Highlights:
Lymphoid Neoplasia: Correlations Between Morphology and Flow Cytometry.
This review describes the cytologic features, flow cytometry immunophenotype, and immunophenotypic prognostic information for 6 major types of canine lymphoma and leukemia.
Comparison of health parameters in normal cats fed a limited iodine prescription food vs a conventional diet.
These results support the lack of obvious side effects associated with feeding a limited iodine diet for 2 years to healthy, adult cats, a situation that may occur in multi-cat households where healthy cats have access to a limited iodine diet being used to manage cats with feline hyperthyroidism.
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Diagnosis and treatment of dermatophytosis in dogs and cats.: Clinical Consensus Guidelines of the World Association for Veterinary Dermatology.
No one diagnostic test was identified as the gold standard. Successful treatment requires concurrent use of systemic oral antifungals and topical disinfection of the hair coat. Wood's lamp and direct examinations have good positive and negative predictability, systemic antifungal drugs have a wide margin of safety, and physical cleaning is most important for decontamination of the exposed environments.
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Almost all veterinary hospitals in this study recommended 12 months of flea and tick prevention, but only 62% of participating dog owners recalled this recommendation. The average owner response was that their dogs require 10.5 months of flea and tick prevention annually. The estimated actual flea and tick prevention coverage was 6.1 months based on owner medication purchases over a 12-month period.

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