Fibroblastic osteosarcoma in a guinea pig (Cavia porcellus)

Braz J Vet Pathol. March 2023;16(1):46-50. 33 Refs

Joerg Richard Vetter¹, Leila Gertrudis Maidana, Roger Gonzalez-Vatteone, César Esteban Brítez-Valinotti, Raquel Ramírez-Diarte

¹ Departamento de Recursos Faunísticos y Medio Natural, Facultad de Ciencias Veterinarias, Universidad Nacional de Asunción, PO BOX 1061, San Lorenzo 2160, Paraguay. jvetter@vet.una.py

Author Abstract

The article describes the case of a 3 year 6 months old Guinea Pig (Cavia porcellus) that was assisted at the Wildlife and Exotic Animal Practice of the Faculty of Veterinary Sciences, National University of Asunción. The patient presented a hard mass in the right hind limb extending from the proximal portion of the femur, projecting caudally to the proximal tuberosity of the calcaneus, with an increase in temperature, and a marked increase in sensitivity. Radiographic diagnosis refers to a mass with amorphous areas of mineral density. Fine needle aspiration puncture revealed an undifferentiated malignant proliferative process, requiring histopathological analysis to characterize the process. Disarticulation was performed and subsequent histopathologic diagnosis under hematoxylin-eosin and Masson’s trichrome stain revealed fibroblastic osteosarcoma.

Keywords

Cavia porcellus, neoplasm, bone, Paraguay

Article Tools:

Email to me

Archives Highlights:

Feline Stress Management During air Travel: A Multimodal Approach.
While the discussion is focused on air travel specifically, the stress management methods described can be applied to all types of longer distance travel, such as a long road trip or a ferry crossing, as well as a stay in a holiday home.

Wavy changes in the whiskers of domestic cats are correlated with feline leukemia virus infection.
The prevalence of wavy whiskers (WW) was significantly correlated with FeLV antigen positivity in the blood. Of 56 cases with WW, 50 (89.3%) were serologically positive for FeLV. The significant association between WW and serological FeLV positivity was also confirmed by multivariate analysis. In WW, narrowing, degeneration, and tearing of the hair medulla were observed. Mild infiltration of mononuclear cells in the tissues, but no degeneration or necrosis, was found. By immunohistochemistry, FeLV antigens (p27, gp70, and p15E) were observed in various epithelial cells including the sinus hair follicular epithelium of the whisker.

Delayed embryonic development or a long sperm survival in two mares-A registration conundrum.
Donor mares were inseminated with semen from one stallion during one oestrous cycle and semen from a different stallion on the subsequent oestrous cycle. Embryo(s) were collected 8?days after ovulation during the second oestrous cycle and transferred into synchronised recipient mares. Genetic testing was performed to determine parentage of the two foals. For both foals, DNA parentage testing excluded the second stallion as the genetic sire and confirmed that the first stallion, whose semen was inseminated on the previous oestrous cycle, was the actual genetic sire.

Head Trauma Management in Small Animals
This article reviews the pathophysiology of head trauma, patient assessment, diagnostic testing, treatment recommendations, monitoring, and prognosis.

Cowpox in zoo and wild animals in the United Kingdom.
We present epidemiological data and diagnostic features of 27 recent, naturally occurring cowpox cases in zoo and wild animals across the UK, including the first reports of cowpox in two snow leopards, a Bengal tiger, three Chilean pudus, a Malayan tapir, and a Eurasian otter, and the first reports of Orthopoxvirus infection in a lar gibbon, a Southern tamandua, and an aardvark.