VIN MULT207-1020: Pathologic Basis of Disease 2020

Module 1 of 7 in the Organ Systems Pathophysiology and ABVP Core Examination Review series.
The lectures for this course will be presented in an audio format using a webinar platform.

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Presenters: Robert M. Gogal Jr., DVM
Beth Davidow, DVM, DACVECC
Sharon Gwaltney-Brant, DVM, PhD, ABVT, ABT
Margret L. Casal, DVM, MS, PhD
Sarah Abood, DVM, PhD
Julie A. Churchill, DVM, PhD, DACVN
Eric Snook, DVM, PhD, DACVP
Scott D. Reed, DVM, PhD, DABVP, DACVP
Marike Visser, DVM

Course Open: October 29, 2020-January 31, 2021
Real Time Sessions (RTS): Thursdays, November 5, 12, 19, December 3, 10, 17, 2020; January 7, 14 and 21, 2021; 9:00-11:00 pm ET (USA)
Course RTS Times in Your Area: World Clock Converter

Level and Prerequisites: This intermediate course will be open to veterinarians actively interested in the pathophysiological basis of disease in small animals based on pathophysiological and discipline-specific concepts.
VIN CE Course: Open to veterinarians. This course has been submitted for RACE approval for veterinarians.

Course Information:
The first of seven modules in the Organ System Pathophysiology and ABVP Core Examination review series, this course is designed to cover the pathophysiological basis of disease in small animals based on pathophysiological and discipline-specific concepts.

It is tour through some aspects of "DAMNITV" in preparation for future modules (which cover diagnosis and a more traditional specialty/body system-based review). Clinical examples will be used to illustrate these concepts; however the focus is on pathophysiology and also on review of certain discipline-specific material, such as pharmacology, that would not otherwise be covered systematically in the later body-system review-based modules.

The Organ System Pathophysiology and ABVP Core Examination Review series of courses may be used as a comprehensive review for the ABVP examination for small animals. This series of courses repeats every other year. Individual instructors may change some of their material year-to-year, but much of the core content is repeated.

It should be noted that these courses are not designed specifically as a preparation for test taking. The instructors do not have access to information on the question types. Furthermore the questions used on the examination may be a few years behind the current knowledge and practice, whereas the course will strive to be more current. We recommend using the course to
  • keep progressing through the topics so all topics will have been studied prior to the exam and
  • provide participants with feedback on their strongest and weakest topics to guide their individual exam specific preparations.

Week 1 (Real Time Session November 5, 2020): Cell Injury and Repair/Death & Inflammation & Modulators
Presenters: Eric Snook and Scott D. Reed
Format: Audio
Objectives: Upon completion of this session, the participant should be able to
  • better understand the acute inflammatory response.
  • better understand chronic inflammation and the outcome of inflammation.
  • understand the role of pathologic calcification

Week 2 (Real Time Session November 12, 2020): Cell Growth and Differentiation - Normal and Neoplastic Transformation
Presenter: Eric Snook
Format: Audio
Objectives: Upon completion of this session, the participant should be able to
  • understand the cell cycle and its relevance to clinic oncology.
  • understand the role of signals for cell growth and differentiation.
  • better understand senescence, apoptosis, and relevance in cancer biology.
  • better understand tumor heterogeneity and resistance to therapy.

Week 3 (Real Time Session November 19, 2020): Principles of Toxicology
Presenter: Sharon Gwaltney-Brant
Format: Audio
Objectives: Upon completion of this session, the participant should be able to
  • understand the factors that influence toxicity.
  • understand toxicokinetics, toxicodynamics and organ system toxicology.
  • understand dose response.

***** BREAK - November 26, 2020 *****

Week 4 (Real Time Session December 3, 2020): Shock
Presenter: Beth Davidow
Format: Audio
Objectives: Upon completion of this session, the participant should be able to
  • define the clinical syndrome known as "shock" in small animal veterinary patients.
  • recognize clinical signs of shock in dogs and cats.
  • differentiate between shock syndromes in dogs versus cats.
  • develop skills to manage shock in both species.

Week 5 (Real Time Session December 10, 2020): Principles of Pharmacology
Presenter: Marike Visser
Format: Audio
Objectives: Upon completion of this session, the participant should be able to
  • define the pharmacokinetic principles from a clinical/case-based perspective.
  • discuss adverse drug reactions and drug-drug interactions.

Week 6 (Real Time Session December 17, 2020): Nutrition
Presenters: Sarah Abood and Julie Churchill
Format: Audio
Objectives: Upon completion of this session, the participant should be able to
  • assess critical factors and build appropriate dietary recommendations.
  • apply practical approaches to using therapeutic diets for clinical cases.
  • take appropriate measures when dealing with suspected pet food recalls.

***** BREAK - December 24 and 31, 2020 *****

Week 7 (Real Time Session January 7, 2021): Genetic Diseases
Presenter: Margret L. Casal
Format: Audio
Objectives: Upon completion of this session, the participant should be able to
  • apply a clinical approach to dealing with genetic diseases.
  • understand how genetic tests are interpreted.
  • understand the role of genetic counseling.
  • understand the purpose of "Mutt" tests and parentage testing.

Week 8 (Real Time Session January 14, 2021): Immunology
Presenter: Robert M. Gogal Jr.
Format: Audio
Objectives: Upon completion of this session, the participant should be able to
  • explain the clinical consequences associated with optimal immune response versus dysregulated immune response.
  • explain the mechanisms that mediate the 4 hypersensitivities and clinical signs of each.
  • explain the differences between primary and secondary immunodeficiency disorders.

Week 9 (Real Time Session January 21, 2021): Veterinary Vaccines
Presenter: Robert M. Gogal Jr.
Format: Audio
Objectives: Upon completion of this session, the participant should be able to
  • explain the rationale for vaccine development.
  • define the meaning of "protection" as it relates to vaccines
  • explain the different forms of vaccines including their advantages and disadvantages
  • understand the origins of vaccines and laws regarding the use of vaccines, both at the federal and state level
  • explain and defend the recommended vaccination protocols.
  • discuss alternate strategies to vaccines.

Successful completion (scoring 80% or better) on the end-of-course test is required to earn a certificate of completion for the course. To learn more about the requirements for earning a CE certificate, please refer to Receiving Your CE Credit and Course Completion Certificate.

Course Materials: Course materials will be available in the course library prior to each Real Time Session.
Required Textbook(s): There is no required textbook for this course.

About the Presenters:
Scott D. Reed is currently a pathologist working for NAMSA, a global medical device testing company. After receiving his DVM at the University of Florida, he spent sixteen years in emergency and primary companion animal practice where he became boarded in canine and feline practice by ABVP (he recertified in 2011). He completed his PhD in cancer immunogenetic therapy and a residency in pathology at LSU and is ACVP boarded in anatomic pathology. Prior to recently joining NAMSA, he served as Laboratory Director and Diagnostic Pathologist at the Tennessee and Texas A&M veterinary diagnostic laboratories respectively. In his free time, Scott enjoys catering to his dogs and working on his tiny hobby farm.

Eric Snook graduated from Iowa State University College of Veterinary Medicine in 2002. He completed a residency in anatomic pathology at LSU in 2009. He received his PhD at Tulane University in 2013 and is currently studying muscular dystrophy as a post-doctoral research associate at TAMU.

Margret L. Casal received her DVM from the University of Zurich in 1984. She also received her MS from University of Bern (1988) and her Ph.D (Pathology) from University of Pennsylvania (1999). She is currently an associate professor of Medicine Genetics at University of Pennsylvania, Penn Veterinary Medicine.

Sarah Abood received her Doctor of Veterinary Medicine degree (1988) from Michigan State University and PhD from The Ohio State University (1997). She was a nutrition scientist at the Ralston Purina Company for 5 years, and Assistant Dean for Student Programs at Michigan State University for 16 years. Since 2018 she has taught nutrition and managed the Clinical Nutrition Service at the Ontario Veterinary College. She has co-authored several articles in peer-reviewed journals, as well as several book chapters and the Manual of Veterinary Dietetics.

Julie A. Churchill received her Bachelor of Science degree and Doctor of Veterinary Medicine degree Michigan State University and her PhD from the University of Minnesota. She is an ACVN diplomate and is currently an Assistant Clinical Professor at the University of Minnesota, Veterinary Medicine Graduate program.

Sharon Gwaltney-Brant earned a BS in zoology and DVM from North Carolina State University. After 3 years in private veterinary practice (companion animal, emergency medicine), she completed a veterinary anatomic pathology residency and earned a PhD in veterinary pathology from Kansas State University. Following a post-doctoral position at the National Animal Disease Center, Dr. Gwaltney-Brant joined the ASPCA Animal Poison Control Center, where she ultimately served as Vice President and Medical Director. She is board certified in veterinary toxicology (ABVT) and general toxicology (ABT). Dr. Gwaltney-Brant currently works as a Toxicology consultant for VIN, performs private Toxicology consulting, and serves as adjunct faculty at the University of Illinois and University of Florida. She currently instructs the Veterinary Forensic Toxicology course for the online Veterinary Forensic Master's degree program through the University of Florida. Dr. Gwaltney-Brant lectures at regional, national and international conferences on veterinary toxicology and veterinary forensic science. She is a charter member and past President of the International Veterinary Forensic Sciences Association.

Marike Visser received her BS in animal science from the University of Kentucky (2008) and DVM from Auburn University (2012). She is currently a clinical pharmacology resident and PhD student at Auburn University.

Robert M. Gogal Jr. received his BS from Virginia Commonwealth University (1982) and his DVM from Virginia Tech (1992). He also received his NIH postdoctoral fellowship at Virginia Tech (1995). Currently, he is a Professor in immunology and immunotoxicology at the University of Georgia with an active teaching assignment in cell biology, small and large animal anatomy, veterinary immunology and clinical immunology. His research focus is in environmental immunotoxicology, cancer immunology with novel drug interactions and autoimmunity, in particular, the effects of environmental contaminants on the immune system during development and through adult life, with a heavy focus on endocrine disruptors across numerous animal models. His lab is presently deciphering the cell signaling pathways associated with consequences of prenatal TCDD exposure and the adult onset of immune disease. To date, he has > 90 peer-reviewed publications and authored one book chapter and has been funded by NIH, DOD, Morris Animal Foundation plus a number of private companies.

Beth Davidow is a 1995 graduate of the College of Veterinary Medicine at Cornell University. She moved to Seattle, Washington after graduation and worked in a primary care small animal and exotic clinic, volunteered at the Woodland Park Zoo, and then started working in an emergency hospital. She realized she was an adrenaline junkie and started an ECC residency at Dove Lewis Emergency Animal Hospital in Portland, OR, passing boards in 2002. She founded Animal Critical Care and Emergency Services (ACCES) in Seattle in 2003, the ACCES Blood Bank in 2004, and a second hospital location, ACCES- Renton in 2010. The hospitals merged with BluePearl in 2013. She served as BluePearl's inaugural Director of Medical Quality in 2017. Dr. Davidow is a Clinical Assistant Professor at Washington State University and the president-elect of ACVECC. She has been a consultant on VIN since 2002. Dr. Davidow is married, has 2 kids, a dog, a rabbit and a bearded dragon. When not working, she enjoys gardening, hiking, swimming, and traveling.

Total CE Credit: 18

Tuition: Member $414 ($373 early bird special if enrolled by October 15, 2020)
Non-Member $584 ($526 early bird special if enrolled by October 15, 2020)
Prices are listed in US dollars.

*Enroll in 3 or more ABVP courses on the same day and receive a 15% discount. This discount does not apply to early bird prices.
  • MULT207-1020: Pathological Basis of Disease
  • MULT208-0221: Principles of Medicine
  • MULT209-0421: Systems A: Organ System Pathophysiology and ABVP Core Examination Review
  • MULT210-0721: Systems B: Organ System Pathophysiology and ABVP Core Examination Review
  • MULT211-1021: Systems C: Organ System Pathophysiology and ABVP Core Examination Review
  • MULT212-0222: Systems D: Organ System Pathophysiology and ABVP Core Examination Review
  • MULT221-0622: Systems E: Organ System Pathophysiology and ABVP Core Examination Review

*To ensure participants are ready and prepared for classes, enrollment will close on November 5, 2020 at 5 pm ET (USA) or when the maximum number of participants is reached.

*For more information on how online CE works, see the Participant Resource Center.

To Enroll:
  1. Enrollment qualifications: VIN CE courses are open to VIN member and non-member veterinarians. Veterinarians enrolling in a VSPN CE course must be a VIN member. Veterinary support staff must be a VSPN member to enroll in a VSPN CE or a VIN CE course open to VSPN member enrollment.
  2. Each enrollee must be able to receive emails from @vspn.org and @vin.com addresses. Email is our major form of communication with participants; personal emails are highly recommended rather than clinic/hospital email addresses.
  3. Each person is individually responsible for his/her own registration. To ensure that all information received is secure and correct, please do not enroll for a course on behalf of another individual.
  4. For further assistance call 800-846-0028 ext. 797 or email . Please include the course title, your full name, and contact information in your correspondence.
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"This program (RACE program number to be determined) has been submitted for approval by AAVSB RACE to offer a total of 18 CE Credits, with a maximum of 18 CE Credits being available to any individual veterinarian. This RACE approval is for the subject matter categories of: Medical, using the delivery method of Interactive-Distance: (Web-based, Teleconference or Audio-Conference). This approval is valid in jurisdictions which recognize AAVSB RACE; however, participants are responsible for ascertaining each board's CE requirements."

Course withdrawal and refund policy: A complete refund of the paid course price will be issued when your withdrawal request is received prior to the listed start date of the course. If you wish to withdraw after the start date please contact the VIN office 800-846-0028 ext. 797 to discuss eligibility for a pro-rated refund.

*For more information on VIN's upcoming CE courses, check the VIN Course Catalog.

Katherine James, DVM, PhD, DACVIM (SAIM)
VIN Education Director

VIN CE Services:
800-846-0028 or 530-756-4881; ext. 797
or direct line to VIN/VSPN from the United Kingdom: 01 45 222 6154
or direct line to VIN/VSPN from Australia: 02 6145 2357