1Veterinary Medical Center, University of Florida, Gainesville, FL, USA; 2Santa Fe Teaching Zoo, Santa Fe College, Gainesville, FL, USA
An adult female, spayed caracal (Caracal caracal) presented with a 3-month history of intermittent anorexia, vomiting and weight loss previously attributed to severe dental disease. After multiple dental extractions, unilateral anterior uveitis with anisocoria developed in the right eye. Examination of the eye under anesthesia revealed copious thick fibrin obscuring the ventral pupil margin and ventral iris in the anterior chamber. There was also a mild amount of pink debris at the ventral aspect of the anterior chamber which appeared to be a mixture of mild hypopyon and hyphema. Examination of the small portion of anterior lens visible through the dorsal pupil margin revealed fibrin on the anterior lens capsule. Fine needle aspiration of the anterior chamber revealed a cytologic diagnosis of granular cell lymphoma. Additional diagnostics (computed tomography and abdominal ultrasound with fine needle aspiration) revealed evidence of metastatic granular cell lymphoma with intestinal perforation and septic peritonitis. Abdominal exploratory with surgical resection was pursued, but the individual was euthanatized when multiple perforations throughout the length of the small intestine were found. Necropsy indicated multicentric lymphoma consistent with metastatic granular cell lymphoma present in the right eye, small intestine, mesenteric lymph nodes and right kidney.