Canine colitis is one of the most common gastrointestinal disorders. It's characterized by tenesmus, dyschezia, hematochezia and presence of mucous in feces. The most common breed affected is the Spaniel Cocker, and stress is the most common cause. The typical treatment consists of the use of metronidazole and Prednisone.
The aim of this investigation is evaluate a new drug, pinaverium bromide like an intestinal calcium channel blocker and its effect for the control of colitis in Spaniel Cocker.
Two hundred and forty two (242) dogs from natural cases were used. They were divided in two groups A and B respectively. A complete anamnesis, clinical history, physical examination and coproparasitoscopic exam was made. All the patients recorded showed tenesmus , hematochezia and mucous in feces.
The group A was treated with Metronidazole 15 mg /kg/12 hours/7 days PO and Prednisone 0.5 mg /kg/12 hours/7 days / PO. The group B was treated with pinaverium bromide 5 mg/kg/24 hours/7 days / PO. In the 7 days treatment, all the patients were fed with a hypoallergenic diet (Royal Canine).
All the patients were reviewed daily. After 7 days treatment the clinical signs in group A disappear in 3 days +/- 0.7 and in group B disappear in 2 days +/- 0.5 (p<0.01 student's test).
No clinical signs relapsed after treatment. No secondary effects were observed.
The use of pinaverium bromide appeared effective and safe for treating colitis in Spaniel Cocker.