Capsule Endoscopy as a Novel Tool for Gastrointestinal Disease Diagnosis in a Puma (Felis concolor)
American Association of Zoo Veterinarians Conference 2017
Jessica N. Lovstad1, DVM; Jill Pomrantz2, DVM, DACVIM; Kathryn C. Gamble1, DVM, MS, DACZM, DECZM (Zoo Health Management)
1Lincoln Park Zoo, Chicago, IL, USA; 2Infiniti Medical, Menlo Park, CA, USA

Abstract

A 10-yr-old, spayed, female puma (Felis concolor) was presented for intermittent hyporexia and vomition of 6 wk duration. Diagnostics, including baseline imaging and clinical pathology, were performed under anesthesia. No conclusive diagnosis was made. As clinical signs persisted an additional 2 wk, the puma was anesthetized for computed tomography, which identified focal thickening at the pyloroduodenal junction (PDJ) and changes in adjacent soft tissue.

The new option of diagnostic imaging by capsule endoscopya presented an opportunity for this case. This technology is an ingestible camera system contained within a 11 mmx31 mm capsule that captures 360° high-resolution images and up to 18 h of data, or approximately 50,000 images.5 The technology has been used in human medicine for nearly 2 decades,4 but only recently become available to veterinarians1-3. In domestic canines greater than 4.5 kg, it has proven a reliable and safe means of diagnosing lesions throughout the gastrointestinal tract and particularly in the small intestine.5 The puma had a 24-h fast from food and then voluntarily ingested the camera in a preferred diet item. The camera was eliminated after approximately 26 h.

During the camera transit, 17,075 images were obtained in 17.7 h of study time. As part of the integrated service for the device, images were interpreted by a veterinary internist, which confirmed thickened gastric mucosa and an apparently healing PDJ ulceration. This easy technique produced high quality images and a diagnosis without the need for additional anesthesia or more invasive diagnostic modalities.

Endnote

a. ALICAM, Infiniti Medical, Menlo Park, CA, USA

Literature Cited

1.  Appleyard M, Fireman Z, Glukhovsky A, Jacob H, Shreiver R, Kadirkamanathan S, Lavy A, Lewkowicz S, Scapa E, Shofti R, Swain P, Zaretsky A. A randomized trial comparing wireless capsule endoscopy with push enteroscopy for the detection of small-bowel lesions. Gastroenterology. 2000;119:1431–1438.

2.  Davignon D, Lee A, Johnston A, Bowman D, Simpson K. Evaluation of a capsule endoscopy to detect mucosal lesions associated with gastrointestinal bleeding in dogs. J Small Anim Pract. 2016;57:148–158.

3.  Hardy B, Gentile-Solomon J, Solomon J. Multiple gastric erosions diagnosed by means of capsule endoscopy in a dog. J Am Vet Med Assoc. 2016;249:926–930.

4.  Iddan G, Meron G, Glukhovsky A, Swain P. Wireless capsule endoscopy. Nature. 2000;405:417.

5.  Pomrantz JS, Hardy BT, Sharma A, Solomon JA. Feasibility of a novel gastrointestinal imaging device for use in dogs. 2016 ACVIM Forum Research Abstract Program. J Vet Intern Med. 2016;30:1462.

 

Speaker Information
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Jessica N. Lovstad, DVM
Lincoln Park Zoo
Chicago, IL, USA


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