Herpes Virus Associated with Mortality in Adult Koi Carp (Cyprinus carpio)
IAAAM 1999
Jill V. Spangenberg1; R.P. Hedrick1; Myron J. Kebus2
1Fish Health Service, Department of Medicine and Epidemiology, University of California Davis, Davis, CA, USA; 2Wisconsin Aquatic Veterinary Service, Madison, WI, USA


Extensive sub-acute mortality amongst koi carp in the Eastern United States prompted field and subsequent laboratory investigations. Epidemiologic history of the outbreak as well as clinical presentation of affected animals suggested a viral etiology. A herpes virus was observed by EM in tissues of affected fish, and was subsequently isolated in cell culture. Initial infectivity trials suggest that the isolated herpes virus does cause the same disease in naïve fish subjected to bath exposure. Primary lesions include disseminated myeloproliferative disease, exocrine pancreatic atrophy, and meningoencephalitis with intra-nuclear inclusion bodies present in neurons. Attempts to re-isolate the virus from experimentally exposed fish are underway. To our knowledge, this represents the first report and investigation of a herpes virus associated with extensive mortality in adult carp, with implications for regulation of shipment and showing of koi carp.


This work was supported in part by a grant from the Associated Koi Clubs of America to the Fish Health Service, University of California, Davis.

Speaker Information
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Jill V. Spangenberg
Fish Health Service, Department of Medicine and Epidemiology
School of Veterinary Medicine, University of California, Davis
Davis, CA, USA

MAIN : Session IV : Herpes Virus
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