Diagnostic Hiccups in Cytology: Poor Slide Preparation and Insufficient Information
Introduction
It will be problematic if a physician sends just some cytologic slides to the laboratory without clinical information. In addition, even a well-trained cytologist can miss a diagnosis if specimens have poor quality. The purpose of this lecture is to introduce important points on requisition form, and major errors on slide preparation. These problems will be demonstrated by related cases with macroscopic and microscopic photographs. Issues of tissue sampling techniques will be talked in the other sessions of this conference.
Poor slide preparation
Naked nuclei: High grade lymphoma
Cell aggregates: Epithelial tumors
Insufficient staining
Low cellularity: Fusiform cell tumors
Insufficient information
Gross morphology: Low grade lymphoma
History: Sarcoma vs. granulation tissue
Site: Thyroid carcinoma
Age: Canine cutaneous histiocytoma vs. plasmacytoma
Species: Dogs vs. cats in mastocytoma
Namba Veterinary Pathological Laboratory, Setagaya Kamiuma 4-2-9-1209, Tokyo, 154-0011, Japan, Email: BZG14356@nifty.com, Web page: http://homepage2.nifty.com/p-tuat-vet/namba/home.html