Effects of Different Dosages of Dopamine and Dubotamin on Dog's E.C.G
World Small Animal Veterinary Association World Congress Proceedings, 2003
Ali Shabestari Asl; Kamal Hasanalizadeh
Small Animal Internal Medicine, Department of Tabriz, AZAD University
Artesh St. Tabriz, Iran

Chronic heart failure therapy used to remove or relief signs of cardiac disorders. Different cardiac inotropic are used for CHF treatment. The usual drug is digoxin but another cardiac inotropic drugs can be used for CHF therapy. Dopamine is one of these drugs that has a copiexity pharmacology. Dobutamine has a direct inotropic effect and is a synthetic analog of dopamine and seems to be a beneficial sympathomimetic amin for CHF treatment.

In this research, we tried to determination of induced E.C.G changes with theses drugs. We selected two independent groups. Each group included ten dogs. We never used any chemical drug for restraining because the sedative drugs affects on cardiac normal function. We obtain an electrocardiogram to determinate any cardiac disorders and dogs with cardiac problems were eliminated. These drugs resolved in dextrose (5%) with three different dilutions. Injectable drugs calculated based on drop per minute. The injection interval of different dilutions were ten minutes. Comparative study on normal electrocardiogram after injection of dopamine and dobutamine, indicates that:

1.  Decrease of S-T segment and innovation of shape of P&T waves.

2.  Exacerbation of normal sinus arrhythmias.

3.  Induced of ectopic atrial and ventricular contractions.

4.  Induced of tachycardia and different cardiac blocks.

Analyzing of statistic data with RB method (random block CRD) shows that:

1.  Decrease of P wave amplitude.

2.  Increase of T wave amplitude.

3.  Decrease of Q-T wave interval because of changes in heart rates.

With attention to effects and analysis of statistic data indicate that dobutamine is a choice drug for emergency treatment for C.H.F and dobutamine suitable cardiogenic shock.

Speaker Information
(click the speaker's name to view other papers and abstracts submitted by this speaker)

Ali Shabestari As
Small Animal Internal Medicine
Department of Tabriz
AZAD University
Artesh St. Tabriz, Iran


MAIN : Cardiology/Pulmonary : Dopamine and Dubotamin
Powered By VIN

Friendly Reminder to Our Colleagues: Use of VIN content is limited to personal reference by VIN members. No portion of any VIN content may be copied or distributed without the expressed written permission of VIN.

Clinicians are reminded that you are ultimately responsible for the care of your patients. Any content that concerns treatment of your cases should be deemed recommendations by colleagues for you to consider in your case management decisions. Dosages should be confirmed prior to dispensing medications unfamiliar to you. To better understand the origins and logic behind these policies, and to discuss them with your colleagues, click here.

Images posted by VIN community members and displayed via VIN should not be considered of diagnostic quality and the ultimate interpretation of the images lies with the attending clinician. Suggestions, discussions and interpretation related to posted images are only that -- suggestions and recommendations which may be based upon less than diagnostic quality information.

CONTACT US

777 W. Covell Blvd., Davis, CA 95616

vingram@vin.com

PHONE

  • Toll Free: 800-700-4636
  • From UK: 01-45-222-6154
  • From anywhere: (1)-530-756-4881
  • From Australia: 02-6145-2357
SAID=27