Correlation between Retinal Morphological Development and Development of the Electroretinogram in the Dog
World Small Animal Veterinary Association World Congress Proceedings, 2003
N. Tuntivanich; S.M. Petersen-Jones
College of Veterinary Medicine, Michigan State University, USA G355, Veterinary Medical Center, Michigan State University
East Lansing, MI, USA


This study was performed to compare the morphological maturation of the retina with its functional maturation in dogs.

Materials & Methods

A scotopic intensity series electroretinogram was recorded weekly following eyelid opening from seven dogs. For retinal morphology, tissues were fixed, plastic embedded and sections taken in a vertical plane through the optic nerve head. The thickness of retinal layers was measured at 8 regions across the retina using Neurolucida software (MicroBrightField).


At 2 weeks of age, the peripheral retina was thicker than the central retina. The photoreceptor inner segments were present and a low amplitude ERG could be recorded. By 4 weeks of age the photoreceptor outer segments had formed but were not fully developed. The photoreceptor cell layer reached maximal thickness at approximately 7 week of age at which time maximal ERG responses were recorded. The photoreceptor cell layer became thinner by 16 weeks of age and this was reflected by a decrease in ERG amplitudes.


The ERG amplitudes correlate with the photoreceptor cell layer thickness. ERG achieves adult waveform as photoreceptor cell layer achieves maximal thickness.

Speaker Information
(click the speaker's name to view other papers and abstracts submitted by this speaker)

Nalinee Tuntivanich
Department of Veterinary Surgery
Faculty of Veterinary Sciences
Chulalongkorn University
Bangkok, Thailand

MAIN : Oral Presentations : Retinal Morphological Development
Powered By VIN

Friendly Reminder to Our Colleagues: Use of VIN content is limited to personal reference by VIN members. No portion of any VIN content may be copied or distributed without the expressed written permission of VIN.

Clinicians are reminded that you are ultimately responsible for the care of your patients. Any content that concerns treatment of your cases should be deemed recommendations by colleagues for you to consider in your case management decisions. Dosages should be confirmed prior to dispensing medications unfamiliar to you. To better understand the origins and logic behind these policies, and to discuss them with your colleagues, click here.

Images posted by VIN community members and displayed via VIN should not be considered of diagnostic quality and the ultimate interpretation of the images lies with the attending clinician. Suggestions, discussions and interpretation related to posted images are only that -- suggestions and recommendations which may be based upon less than diagnostic quality information.


777 W. Covell Blvd., Davis, CA 95616


  • Toll Free: 800-700-4636
  • From UK: 01-45-222-6154
  • From anywhere: (1)-530-756-4881
  • From Australia: 02-6145-2357