Incidence of Neoplasia in a Colony of Captive Felids at the Knoxville Zoological Park, 1979–2003
American Association of Zoo Veterinarians Conference 2005

Michael A. Owston1, MS, DVM; Edward C. Ramsay2, DVM, DACZM; David Rotstein3, DVM, MPVM, DACVP

1Department of Veterinary Pathobiology, Purdue University, West Lafayette, IN, USA; 2Department of Small Animal Clinical Sciences, College of Veterinary Medicine, The University of Tennessee, Knoxville, TN, USA; 3Department of Pathobiology, College of Veterinary Medicine, The University of Tennessee, Knoxville, TN, USA


A review of medical records and necropsy reports found neoplasms in 27 zoo felids including 6 Panthera leo (3 males, 3 females), 3 Panthera pardus (2 males, 1 female), 1 Panthera onca (1 female), 11 Panthera tigris (3 males, 8 females), 2 Panthera uncia (1 male, 1 female), 2 Felis concolor (1 male, 1 female), 1 Felis rufus (1 male), and 1 Acinonyx jubatus (1 female). Neoplasia rate at necropsy was 43% (25/58), and overall rate of neoplasia in the collection was 21% (27/130). Neoplasia was identified as the cause of death or reason for euthanasia in 21% (12/58) of those necropsied. Neoplasms were observed in the endocrine (n=11), integumentary (n=11), reproductive (n=7), hematopoietic/lymphoreticular (n=5), digestive (n=2), hepatobiliary (n=2), and respiratory (n=1) systems. Multiple neoplasms were observed in 10 animals. Both benign and malignant neoplasms were observed in all systems except for the respiratory and hematopoietic/lymphoreticular systems where the process was benign in the former and malignant in the latter. Of the endocrine neoplasms, those involving the thyroid and parathyroid glands predominated (n=10) over other endocrine organs (n=1) and ranged from hyperplasia to carcinoma. In the digestive system, only the pancreas had neoplasms present. Both hepatobiliary tumors involved the biliary tree. In the integumentary system, 63% (7/11) of neoplasms involved the mammae with mammary carcinoma representing 83% (6/7) of neoplasms. The only respiratory tumor was a benign laryngeal papilloma. Hematopoietic/lymphoreticular tumors included lymphosarcoma (60%, 3/5) and mast cell tumor (40%, 2/5). Leiomyomas (60%, 3/5) and uterine adenocarcinomas (40%, 2/5) were observed in the female reproductive system, and seminomas were observed in the male reproductive system.


Speaker Information
(click the speaker's name to view other papers and abstracts submitted by this speaker)

Michael A. Owston, MS, DVM
Department of Veterinary Pathobiology
Purdue University
West Lafayette, IN, USA

MAIN : 2005 : Neoplasia Incidence in a Colony of Captive Felids
Powered By VIN