Prevalence of Autosomal-Dominant Polycystic Kidney Disease (PKD) in Persian Cats (Originated from Iran) in Tehran, Iran
S. Nikkhah1; M. Bitaraf2; S. Habib Savijbolaghy3; M. Ferdows2; V. Fathipoor4; S.J. Ale Davod5
Introduction
Many reports of congenital renal cysts in cats have been published. PKD is inherited as an autosomal-dominant trait in Persian cats.
Objectives
In this study, we want to determine the prevalence of the disease in Persian cats in Tehran, to alert veterinary practitioners to the prevalence of PKD, and to propose methods of eliminating the disease from future generations of cattery-bred cats.
Methods
To be included in this plan, cats had to be Persian and be older than 6 months of age. Younger cats were excluded because of the increased likelihood of a false-negative result. Renal ultrasonography was performed using 5–8-MHz microconvex transducer and 8–10-MHz linear transducer.
Results
A total of 123 Persian cats were tested. The prevalence of autosomal-dominant polycystic kidney disease was 22.7%, and no sex predilection was identified.
Conclusions
According to the prevalence of PKD, it has been observed to be 35% to 57% in Persian cats surveyed by ultrasonography.1 These results show that the prevalence of autosomal-dominant polycystic kidney disease in Iran is low, which may be associated with domicile, environment, nutrition, etc. and needs more evaluation in the future.
Reference
1. Familial renal disease in dogs and cats. In: Ettinger SJ, Feldman EC. Textbook of Veterinary Internal Medicine: Diseases of the Dog and Cat. 7th ed. St. Louis, MO: Elsevier Saunders; 2010:1823 (chapter 257).