Efficacy of Various Therapeutic Agents Against Sarcoptic Mange in Dogs
World Small Animal Veterinary Association World Congress Proceedings, 2015
S. Roy1; M. Roy2; K.T.V. Ajay1; T. Ottalwar1
1Veterinary Medicine, College of Veterinary Science and Animal Husbandry, Bhilai, India; 2Veterinary Biochemistry, College of Veterinary Science and Animal Husbandry, Bhilai, India

Introduction

Sarcoptic mange is a highly contagious and pruritic acariosis of the skin characterized by intense pruritus vesiculopapular eruptions with alopecia.

Objectives

To compare therapeutic efficacy of various agents against sarcoptic mange-infected dogs

Methods

Experimental design

Group

No. of dogs

Treatment

A

6

Ivermectin at 200 μg/kg bodyweight. Orally

B

6

Ivermectin treatment + topical application of Annona squamosa leaves

C

6

Topical application of Annona squamosa leaves

D

6

Azadirachta indica and Curcuma longa paste (4:1) topical application

Therapeutic efficacy of the different treatment regimen was evaluated on the basis of clinical improvement, negative skin scraping, and restoration of hematological parameters, oxidative stress and trace mineral status.

Results

Macroscopical examination of skin scrapings of dogs with sarcoptic mange revealed the presence of very high numbers of eggs, developing and adult mites per microscopic field before the start of the therapy. Hematological study revealed significantly (p ≤ 0.05) decreased levels of hemoglobin, PCV, and total erythrocyte count before treatment and restoration of values are observed in group B animals. Total leukocyte count was increased in infected dogs and the level decreased significantly after therapy in all the treated groups. Results of the present study showed restoration of sarcoptic mange induced oxidative stress and plasma zinc and iron levels.

Conclusion

In conclusion, ivermectin and Annona squamosa leaf extracts have remarkable restoration potential contributing to the deterrence of Sarcoptes-induced alterations in dogs.

  

Speaker Information
(click the speaker's name to view other papers and abstracts submitted by this speaker)

S. Roy
Veterinary Medicine
College of Veterinary Science and Animal Husbandry
Bhilai, India


MAIN : Dermatology : Various Therapeutic Agents Against Sarcoptic Mange
Powered By VIN

Friendly Reminder to Our Colleagues: Use of VIN content is limited to personal reference by VIN members. No portion of any VIN content may be copied or distributed without the expressed written permission of VIN.

Clinicians are reminded that you are ultimately responsible for the care of your patients. Any content that concerns treatment of your cases should be deemed recommendations by colleagues for you to consider in your case management decisions. Dosages should be confirmed prior to dispensing medications unfamiliar to you. To better understand the origins and logic behind these policies, and to discuss them with your colleagues, click here.

Images posted by VIN community members and displayed via VIN should not be considered of diagnostic quality and the ultimate interpretation of the images lies with the attending clinician. Suggestions, discussions and interpretation related to posted images are only that -- suggestions and recommendations which may be based upon less than diagnostic quality information.

CONTACT US

777 W. Covell Blvd., Davis, CA 95616

vingram@vin.com

PHONE

  • Toll Free: 800-700-4636
  • From UK: 01-45-222-6154
  • From anywhere: (1)-530-756-4881
  • From Australia: 02-6145-2357
SAID=27