Analgesic Effects of Firocoxib in Cats after Ovariohysterectomy
World Small Animal Veterinary Association World Congress Proceedings, 2015
P. Phuwapattanachart; N. Thengchaisri
Department of Companion Animal Clinical Sciences, Kasetsart University, Bangkok, Thailand


Various analgesic agents including non-steroidal anti-inflammatory drugs (NSAIDs) have been shown to be effective for pain control in cats. Firocoxib, a NSAIDs classified as a selective COX-2 inhibitor, has been successfully used in dogs; however, the efficacy of firocoxib in cats remains elusive.


The purpose of a present study was to study the post-operative analgesic effects of firocoxib in cats undergoing ovariohysterectomy.


Twenty-four cats were divided into 3 groups including a control (no medicine), a firocoxib-1 (1 mg/kg/day) and a firocoxib-3 (3 mg/kg/day). The NSAIDs were given at 1 h before induction with propofol 4–6 mg/kg IV, followed by anesthesia maintenance with isoflurane. Colorado pain scores were recorded in blinded fashion before induction (base line) and 2, 5, 8, 24, 30, and 48 hours following the recovery.


The average baseline of Colorado pain scores from control, firocoxib-1 and firocoxib-3 groups were not different (0.4 ± 0.2, 0.3 ± 0.1, and 0.5 ± 0.2, respectively; p-value > 0.05). The average Colorado pain scores recordings to 48 hours post-operation from firocoxib-3 groups (0.4 ± 0.1) were significantly lower than that of control group (0.7 ± 0.2; p-value = 0.004). However, no significant difference was found between the average pain scores of firocoxib-1 (0.5 ± 0.2) and control groups (p-value = 0.12). One cat from firocoxib-3 treated group vomited one time at 48 hours post-operation.


The present study suggests that firocoxib-3 is helpful for post-operative pain control in cats; however, gastrointestinal irritation due to the use of NSAIDs may occur.


Speaker Information
(click the speaker's name to view other papers and abstracts submitted by this speaker)

P. Phuwapattanachart
Department of Companion Animal Clinical Sciences
Kasetsart University
Bangkok, Thailand

MAIN : Pain Management : Analgesic Effects of Firocoxib
Powered By VIN

Friendly Reminder to Our Colleagues: Use of VIN content is limited to personal reference by VIN members. No portion of any VIN content may be copied or distributed without the expressed written permission of VIN.

Clinicians are reminded that you are ultimately responsible for the care of your patients. Any content that concerns treatment of your cases should be deemed recommendations by colleagues for you to consider in your case management decisions. Dosages should be confirmed prior to dispensing medications unfamiliar to you. To better understand the origins and logic behind these policies, and to discuss them with your colleagues, click here.

Images posted by VIN community members and displayed via VIN should not be considered of diagnostic quality and the ultimate interpretation of the images lies with the attending clinician. Suggestions, discussions and interpretation related to posted images are only that -- suggestions and recommendations which may be based upon less than diagnostic quality information.


777 W. Covell Blvd., Davis, CA 95616


  • Toll Free: 800-700-4636
  • From UK: 01-45-222-6154
  • From anywhere: (1)-530-756-4881
  • From Australia: 02-6145-2357