The Sertoli cell tumor is considered one of the three main testicular tumors in dogs. These tumors occur more frequently in cryptorchid animals and are generally locally invasive but rarely metastatic.
To describe a metastatic Sertoli cell tumor in left kidney
A six-year-old, mongrel dog was treated at the Veterinary Hospital of São Paulo State University - Jaboticabal, Brazil, presenting with bilateral cryptorchidism, increased abdominal volume, apathy, anorexia and dyschezia. Blood count, biochemical analysis, and abdominal ultrasound were performed.
The ultrasound detected a mass occupying most of the cavity, presenting an anechoic formation and different echogenicity structures, moving all the organs of the abdominal cavity. Exploratory laparotomy showed a mass measuring approximately 40 x 40 x 20 cm in the left ectopic testis with metastasis in the left kidney and ureter. Right testicle was stunted. Orchiectomy and left nephrectomy were performed. After histopathological examination, the presence of malignant neoplasia was confirmed on testicles and kidney fragments. The patient was subjected to alternating chemotherapy of doxorubicin and carboplatin, every 21 days doses.
Left testis (A); right testis (B); left kidney (C)
There are only a few studies on the metastatic potential of sertolioma and chemotherapy protocols, often making necessary to extrapolate treatment from human medicine. In this case, the dog showed a significant clinical and laboratory improvement, no side effects related to chemotherapy, and to date is in complete remission.