Jeffrey Slutsky; Karthik Raj; Scott T. Yuhnke; Urs Giger; WSAVA Hereditary Disease Committee
Section of Medical Genetics (PennGen), School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA
Following the first identification of a disease-causing mutation in dogs in 1989, and the more recent completion of the canine and feline genome sequences, much progress has been made in the molecular characterization of hereditary diseases in dogs and cats.
To increase access to information on diagnosing hereditary diseases in dogs and cats, a web application has been developed to collect, organize, and display information on available DNA tests and other supporting information, including gene and chromosomal locations, mutations, primary research citations, and disease descriptions. The DNA testing information can be accessed at PennGen under the tab 'Tests Available at Labs Worldwide' at the URL: http://research.vet.upenn.edu/WSAVA-LabSearch. There are currently 170 molecular genetic tests available for hereditary diseases in dogs and cats offered by 54 laboratories worldwide.
This tool should provide clinicians, researchers, breeders, and companion animal owners with a single comprehensive, up-to-date, and readily searchable webpage for information regarding hereditary disease testing.
Supported in part by the WSAVA Hereditary Disease Committee, Waltham and NIH OD 010939.