An Evaluation of 9,570 Dogs by Breed and Dog Erythrocyte Antigen Typing
ACVIM 2008
A.S. Hale1; J. Werfelmann1; M. Lemmons2; B. Smiler2; J. Gerlach2
1Midwest Animal Blood Services, Inc., Stockbridge, MI, USA; 2Michigan State University, East Lansing, MI, USA

Nine thousand five hundred and seventy dogs were evaluated by breed and dog erythrocyte antigen assay (DEA) for the purpose of predicting compatibility during routine transfusion service.

Retrospectively, data from these dogs was evaluated for DEA frequency in relation to breed type and total incidence within the submitted population. Sample testing occurred between 1995 and 2006. All dogs were evaluated for DEA by tube agglutination utilizing polyclonal antisera derived through canine alloimmunization recognizing DEA 1.1, 1.2, 3, 4, 5 and 7. Ninety breeds were represented. All recognized AKC breed groups were represented in the sampling. Data from mixed breed dogs was also correlated. Population incidence for the total sampling is represented in the table below.

DEA antigen

Population frequency

1.1

42%

1.2

12%

3

7%

4

98%

5

11%

7

20%

Twenty nine percent of all dogs tested positive for DEA 4 only ("Universal" type). Breeds demonstrating an incidence of "universal" type greater than the average population frequency included Airedale, American Bulldog, Boxer, Bull Mastiff, English Bulldog, English Mastiff, German Shepherd, Greyhound, Irish Wolfhound, Old English Sheepdog, Pit-bull, Saluki and Scottish Deerhound. Twenty six percent of all dogs tested positive for DEA 1.1 and 4 only. Breeds demonstrating an incidence of DEA 1.1,4 greater than the average population frequency included Afghan, Bassett Hound, Bernese Mountain Dog, Border Collie, Bouvier des Flandres, Bullmastiff, Bull Terrier, Chesapeake Bay Retriever, Cocker Spaniel, Dalmatian, English Mastiff, English Setter, English Springer Spaniel, Great Dane, Golden Retriever, German Shorthair Pointer, Great Pyrenees, Irish Setter, Labrador Retriever, Malamute, Malinois, Newfoundland, Poodle, Rottweiler, Samoyed, St Bernard, Standard Poodle and Vizsla. Using the currently recommended field typing scheme, 55% of all dogs submitted for typing could be used as a red blood cell donor without DEA mismatch if the recipients are type matched for DEA 1.1.

Speaker Information
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Anne Hale


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