Virological Studies in Dolphins
IAAAM Archive
M.M. Sigel, PhD1; J.C. Lee1; W.G. Gilmartin2
1University of Miami School of Medicine, Miami, FL; 2Naval Undersea R & D Center, Point Mugu, CA

Following the instillation of live influenza type A2 (Hong Kong) virus into the respiratory tract, dolphins developed high antibody titers measured by the hemagglutination-inhibition and complement fixation tests. The sera of dolphins are usually anticomplementary but this activity could be removed by precipitation at low iconicity. The earliest antibody was a macroglobulin and with time there was a shift to formation of antibodies of the 7 S class.

Sera from several dolphins and from a killer whale reacted in the complement fixation test with the antigens of adenovirus, type 4, Coxsackie virus, type A7, poliovirus, type I, and mumps virus.

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M. M. Sigel, PhD


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