A male spayed 4 years old terrier dog weighting 4900 gr was presented to the small animal hospital of Tehran university with the history of abdominal skin pruritis, anorexia treated for ectoparasites one week before referring to the hospital. In primary physical examination severe abdominal erythema with yellowish to green skin discharge, pustules, abdominal skin slough, superficial skin necrosis, tachypnea, tachycardia, pyrexia (39.8 centigrade degree) was revealed. Hemogram result was: PCV: 36%, WBC: 3500, neutrophil: 60%, band: 2%, lymphocyte: 31%, eosinophil: 5%, monocyte: 2%, total protein: 7gr/dl. In biochemistry profile, hepatic and renal factors were in normal range. The dog suffers from leucopenia and regenerative anemia. Numerous white blood cells, RBC and cocci shape bacteria were seen in microscopic evaluation of the stump skin sample. Fungal culture was negative and pseudomonas aeruginosa detected as the dominant infective agent in the bacterial culture. Medical therapy with parentral and topical gentamicin, diluted white vinegar (10%), and levamisole by the immuno stimulatory dosage (2.2 mg/kg po q 48 h for 3 weeks) was prescribed. There were significant improvement after one week and the leukogram was normal after 2 weeks.
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