FDA has become increasingly involved in aquaculture in the past several years, with a primary focus on the regulation of drug use in fish intended for human consumption. FDA's focus on aquaculture has necessarily expanded to include nonfood fish species as well and the Agency is currently developing policies for regulation of drug use in non-food fish. Generally, non-food fish include ornamental and aquarium species, certain species of baitfish, and endangered aquatic species.

FDA approval may be required for certain drugs which have been readily available in the past for use in non-food fish. A number of drugs which have previously been available over-the-counter may require a prescription from a veterinarian. Consequently, the demand for veterinary involvement in non-food fish industries may increase as access to some drugs becomes limited.