Interest has been expressed regarding the potential for transmission of zoonotic diseases between dolphins and man through the facilitation of inwater training activities and those which involve water encounter oriented public display. In an attempt to separate fact from presumption, a literature survey was conducted and a number of experienced professionals were consulted. The result of the information search presented here details a notable absence of reports of such transmission of disease, with a few exceptions where occupational exposure was documented. The analysis summarized here would indicate that the zoonotic transmission of disease in these transient encounters between cetaceans and humans does not represent a significant concern to either party.