Five days after the onset of acute iritis, hyphema was seen in the form of both fresh and clotted blood in the anterior chamber of a female Sea Otter (Enhydra lutris) in a small breeding collection at The Seattle Aquarium. Treatment consisted of subconjunctival injection of mydriatic and corticosteroid drugs under general anesthesia. Recurrence two weeks later was treated in the same way. Response to therapy was rapid and judged beneficial in both procedures. Trauma is considered the most likely cause of both episodes.