OBJECTIVES

The aim of this study was to evaluate the effects of iohexol subarachnoid application in the electrocardiography of dogs anesthetized with sevoflurane.

MATERIALS

Fifteen adult healthy male and female mongrel dogs were used. The anesthetic induction was made, through mask, using sevoflurane at 2.5 MAC diluted at 1 l/min oxygen (O2). After intubation, the O2 was adjusted to 30 ml/kg/min and the vaporizer to 1.5 MAC. The dogs were positioned at left lateral recumbency with the heads elevated 30° degree from the table and remained at this position during all the experimental period. After 30 minutes, the liquor was collected (0.3 ml/kg) from the magne cistern at subarachnoid space. Immediately after, the iohexol 30% (0.3ml/kg) was injected slowly. The electrocardiographic study was done in the D2 lead during the whole experimental period. The amplitude and duration of the electrocardiographic waves and heart rate were measured. The measurements were realized at: M1 - immediately before the drugs administration; M2 - 30 minutes after the induction; M3 - immediately after iohexol administration; and at each 10 minutes after M3 (M4, M5, M6, M7, M8, and M9). The numerical data were submitted to Tukey test (p<0.05).

RESULTS

It was not possible to detect significant differences between the groups, during the experimental period, neither among the moments in each group. All the values remained constant without significant physiological or statistical alterations.

CONCLUSION

The results allow us to conclude that the iohexol subarachnoid application in dogs anesthetized with sevoflurane didn't cause significant electrocardiographic alterations.