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ABSTRACT OF THE WEEK

Topics in companion animal medicine.
Volume 66 | Issue 0 (2025 May-Jun)

Case series of maggot debridement therapy demonstrates safety and efficacy for treating problematic wounds in cats and dogs in Mexico.

Top Companion Anim Med. 2025 May-Jun;66(0):100964.
Alicia Fonseca-Muñoz1, Aremí C Lujano-Guzmán2, Albert Nguyen3, Ronald A Sherman4
1 Faculty of Biological Systems and Technological Innovation, Universidad Autónoma Benito Juárez de Oaxaca (UABJO), Av. Universidad S/N. Ex-Hacienda 5 Señores, Oaxaca, México. C.P. 68120.; 2 Advanced Wound Management in Veterinary Medicine, Manejo Avanzado de Heridas en Veterinaria (MAHVET), 46 A Baja California, Roma Sur Mexico City, Mexico. C.P. 06760.; 3 BioTherapeutics, Education & Research (BTER) Foundation, 36 Urey Court, Irvine, CA, U.S.A. 92617.; 4 BioTherapeutics, Education & Research (BTER) Foundation, 36 Urey Court, Irvine, CA, U.S.A. 92617. Electronic address: rsherman@uci.edu.
Copyright © 2025 The Author(s). Published by Elsevier Inc. All rights reserved.

Abstract

Wound care is a common problem in small animals. Antimicrobial resistance, biofilm, time constraints, and the cost of surgery or specialized dressings hinder efforts to deliver prompt wound healing. Maggot therapy has been very effective in human and equine wound care, but very little research has evaluated its safety and efficacy in dogs and cats. This study was initiated to evaluate the utility, efficacy, and safety of maggot debridement therapy for wound care in a small animal veterinary practice in Mexico. Six cats and four dogs were treated with maggot debridement therapy when their wounds failed to respond to conventional therapy. Treatment was administered by applying 8-10 larvae per cm2 surface area directly on the wound bed and covering the wound with a sterile polyester mesh, sutured to the skin. These were left on the wound for cycles of approximately 48 h (24-72 h); the cycles were repeated if >20 % necrotic tissue remained after treatment. Review of these cases revealed that 80 % of treated wounds achieved 100 % debridement within 48-96 h of treatment. An additional 10 % (one wound) achieved 80 % debridement within only 24 h of treatment. One animal failed to show improvement: a 3-year-old cat with an infected bite wound, which drained voluminously and drowned the maggots. This animal was deemed not to be an appropriate candidate for maggot debridement therapy, and treatment was terminated after just 12 h. Ultimately, this wound was debrided and closed surgically. No complications were encountered other than mild discomfort in one cat. These results support claims that maggot debridement therapy is relatively safe and effective for treating problematic dog and cat wounds. Veterinarians should consider including maggot debridement among their treatment options for problematic wounds. Controlled clinical trials should be performed.

Keywords
Biological therapy; Cats; Dogs; Larva; Maggot therapy; Wounds;

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