"My Bitch Is Empty!" An Overview of the Reasons for Pregnancy Loss in Dogs.

Vet Sci. February 2025;12(2):.

George Mantziaras¹, Maja Zakošek Pipan²

¹ Independent Researcher, Small Animal Practitioner, Kifisias Avenue 22, 15125 Marousi, Greece.; ² Clinic for Reproduction and Large Animals, Veterinary Faculty, University of Ljubljana, Gerbičeva 60, 1000 Ljubljana, Slovenia.

Abstract

The purpose of this review is to present reasons for pregnancy loss in dogs. Termination of pregnancy can occur at any stage of gestation, sometimes even before pregnancy is diagnosed. If embryonic death occurs before day 35 of gestation, the embryo is absorbed. Fetal death in the second half of gestation leads to abortion or fetal emphysema, maceration, or mummification. Abnormal embryonic development, competition between placental sites, or genetic abnormalities of the embryo(s) can lead to termination of pregnancy. Maternal factors that alter ovarian function or the environment in the oviducts and uterus, such as cystic endometrial hyperplasia or inflammation, can lead to pregnancy loss. Abnormalities of the placenta, uterine torsion, metrocoele, environmental stress, and malnutrition can have detrimental effects on fetal development. Several drugs or medications can also have embryotoxic/teratogenic effect. Endocrinological disorders such as hypoluteodism, gestational diabetes, and hypothyroidism can be reasons for pregnancy failure. Several bacteria, protozoa, and viruses can cause pregnancy loss in dogs. Etiological diagnoses of pregnancy loss in dogs are challenging as the exact causes are not always obvious; so, a multi-faceted approach is required.

Keywords

abortion; canine pregnancy; endometritis; infertility; resorption;

Article Tools:

Medline

Email to me

Archives Highlights:

Recovery of ambulation in small, nonbrachycephalic dogs after conservative management of acute thoracolumbar disk extrusion.
Forty-nine of fifty-one (96%) of deep pain-positive and 10/21 (48%) of deep pain-negative dogs recovered ambulation within the 12-week period. The median time to ambulation was 11 and 25 days for deep pain-positive and -negative dogs, respectively. Reduction in spinal cord compression varied among individuals from minimal to complete and apparently was unrelated to the recovery of ambulation.

How to plan and provide general anesthesia for a troop of 98 hamadryas baboons (Papio hamadryas) for contraceptive and preventative health interventions.
A group of 12 veterinarians, 2 zookeepers, and 6 volunteers anesthetized all animals within 2 days. The baboons were orally premedicated with midazolam (0.1 to 0.5 mg/kg) and anesthetized with medetomidine (40 to 60 µg/kg, IM) and ketamine (2 to 4 mg/kg, IM); isoflurane at rates of 1.5% to 2% was used for maintaining anesthesia if necessary. For population management, the animals received a contraceptive implant (adult females), orchiectomy (young males), or vasectomy (breeding males).

The Prevalence and Diagnosis of Feline Heartworm Infection
Visualization of supposed worm structures on echocardiography, in conjunction with a positive antigen test result, is as close to a definitive antemortem confirmation of adult heartworm infection as can be achieved.

National survey reveals elastic price sensitivity for select equine veterinary services.
Willingness-to-pay questions were presented with a payment card approach and addressed 3 common services: annual spring vaccinations, lameness examinations, and emergency colic surgeries. In a payment card approach, respondents choose from among preselected values. Respondents were asked to choose the maximum amount they would be willing to pay for each service.

Efficacy and safety of once daily oral administration of sodium-glucose cotransporter-2 inhibitor velagliflozin compared with twice daily insulin injection in diabetic cats.
On Day 45, 29/54 (54%) velagliflozin-treated cats and 26/62 (42%) Caninsulin-treated cats showed treatment success, demonstrating noninferiority. By Day 91, quality of life (QoL), polyuria, and polydipsia had improved in 81%, 54%, and 61% (velagliflozin); on blood glucose (BG) curves, mean BG was <252 mg/dL in 42/54 (78%; velagliflozin) and 37/62 (60%; Caninsulin); minimum BG was <162 mg/dL in 41/54 (76%; velagliflozin) and 41/62 (66%; Caninsulin); serum fructosamine was <450 µmol/L in 41/54 (76%; velagliflozin) and 38/62 (61%; Caninsulin).