Case Series: Computed Tomography Features of Extraskeletal Osteosarcoma in Six Dogs.
Vet Sci. May 2024;11(6):.
Jeongyun Jeong1, Minjoo Kim2, Sung Soo Kim3, Hyunju Hwang4, Joohyun Jung5, Noh-Won Park6, JaeHwan Kim7, Kidong Eom8 1 Department of Veterinary Medical Imaging, College of Veterinary Medicine, Konkuk University, Seoul 05029, Republic of Korea.; 2 Shine Animal Medical Center, Seoul 05550, Republic of Korea.; 3 VIP Animal Medical Center, Seoul 02830, Republic of Korea.; 4 VIP Animal Medical Center, Seoul 02830, Republic of Korea.; 5 Ilsan Animal Medical Center, Ilsan 10368, Republic of Korea.; 6 Nowon N Animal Medical Center, Seoul 01704, Republic of Korea.; 7 Department of Veterinary Medical Imaging, College of Veterinary Medicine, Konkuk University, Seoul 05029, Republic of Korea.; 8 Department of Veterinary Medical Imaging, College of Veterinary Medicine, Konkuk University, Seoul 05029, Republic of Korea.
Abstract
The objective of the present case series was to investigate the various computed tomography findings of six dogs diagnosed with extraskeletal osteosarcoma (exOSA) at several locations. Among the tumors evaluated, four were subcutaneous, one was mammary, and one involved the intestinal tract. Intralesional mineralization was observed in all six dogs. Most of the tumors were moderately calcified, exhibited amorphous mineralization, and were heterogeneous on post-contrast imaging. Three of the tumors were peripherally enhanced, and regional lymphadenopathy was identified in two of the dogs, which was presumed to be metastatic. No lymph node calcification was reported. Although the presence of intralesional mineralization is not a pathognomonic finding, it was consistently identified in the present case series. Therefore, exOSA should be considered in the differential diagnosis when mineralization occurs in a mass unrelated to osseous structures.
Keywords

computed tomography;
extraskeletal osteosarcoma;
metastasis;
mineralization;
peripheral rim enhancement;
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