Reversible control of reproduction in tom cats: medical options for manipulating libido and fertility.

J Feline Med Surg. May 2023;25(5):1098612X231171406.

Lluis Ferré-Dolcet¹, Stefano Romagnoli²

¹ San Marco Veterinary Clinic and Laboratory, Padova, Italy.; ² Department of Animal Medicine, Production and Health, University of Padova, Italy.

Abstract

BACKGROUND:There has been a growing interest in alternatives to surgery for controlling reproduction in tom cats, and the resultant medical options add to a practitioner's toolbox when handling these cases in clinical practice. It is important, however, that when suggesting these drugs, veterinarians have a good understanding of their mode of action, and their correct use and dosage.

CLINICAL RELEVANCE:Breeders increasingly wish to be able to switch on/off the reproductive ability of their tom cats in a controlled manner. In addition, in small animal medicine, there has been concern from some academics, and a growing number of pet cat owners, about potential long-term effects of surgical sterilisation. Further, for some cats surgical castration may not be possible due to health conditions that mean anaesthesia is unsafe. In all of these scenarios, medical alternatives to surgery can prove useful.

EQUIPMENT AND TECHNICAL SKILLS:No special equipment or technical skills are required. A good knowledge of the medical alternatives to surgical sterilisation for controlling reproduction in a tom, and making sure the patient is a suitable candidate, are, however, important for ensuring the cat's health during and after treatment and the owner's satisfaction.

AUDIENCE:This review is aimed principally (but not exclusively) at veterinary practitioners working with cat breeders who seek a temporary arrest in their tom cat's reproduction. It may also help practitioners with clients who would like an alternative to surgery or with cats where anaesthesia for surgical castration is not possible.

EVIDENCE BASE:Advances in reproductive feline medicine have resulted in improved knowledge of medical contraception. This review draws on scientific evidence-based papers that report on the mode of action, length of efficacy and potential side effects of different methods of medical contraception, as well as the authors' own clinical experience.

Keywords

GnRH agonists; GnRH antagonists; Medical contraception; deslorelin; immunocontraception; melatonin; progestogens;

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