Effectiveness of a Modified Administration Protocol for the Medical Treatment of Feline Pyometra.

Vet Sci. September 2022;9(10):.

Simona Attard¹, Roberta Bucci², Salvatore Parrillo³, Maria Carmela Pisu⁴

¹ Palermovet-Centro Diagnostico Veterinario, 90125 Palermo, Italy.; ² Animals Theriogenology Service, Veterinary Teaching Hospital, Faculty of Veterinary Medicine, University of Teramo, Piano d'Accio, 64100 Teramo, Italy.; ³ Animals Theriogenology Service, Veterinary Teaching Hospital, Faculty of Veterinary Medicine, University of Teramo, Piano d'Accio, 64100 Teramo, Italy.; ⁴ VRC-Centro di Referenza Veterinario, 10138 Torino, Italy.

Abstract

Pyometra is a common uterine disease of dogs and cats, typical of the luteal phase. Traditionally, ovariohysterectomy was considered the elective treatment for pyometra, but in some cases, such as breeding subjects or patients with a high anesthesiologic risk, medical treatment is preferred. Aglepristone is a progesterone receptor blocker and its use proved to be effective for the medical treatment of pyometra in bitches and queens. The aim of this work is to report the effectiveness, in the feline species, of a modified aglepristone administration protocol. Five intact queens were referred to veterinary care centers for pyometra. Aglepristone (15 mg/kg) was administered at D0, D2, D5, and D8, as described by Contri and collaborators for dogs. An antibiotic treatment (marbofloxacin, 3 mg/kg) was associated, and uterine conditions were checked with regular ultrasonographic exams. The uterus returned to its normal condition 10 days after starting the treatment and no adverse effects were reported. After treatment, three queens had an uneventful pregnancy. Even if the treated group was restricted and homogeneous, the proposed modified protocol proved to be useful and promising for the medical treatment of pyometra in cats; further studies are planned to verify its effectiveness in the long-term prevention of recurrence.

Keywords

aglepristone; cat; modified treatment; pyometra;

Article Tools:

Medline

Email to me

Archives Highlights:

Development of a dog owner caregiving style scale (Lincoln Owner Caregiving Questionnaire, LOCQ) and its relationship with behaviour problems in dogs
Compared to owners of dogs without behaviour problems, owners with high scores for the Disorganised caregiving style predicted dogs with separation related problems or with more than one behaviour problem, owners with high Avoidant caregiving style scores predicted dogs with Fear, and owners with high scores for both Disorganised and Avoidant caregiving styles predicted dogs with Aggressivity problems.

[Disease Caused by Filoviruses: An Update].
The Marburg and Ebola viruses belong to the Filoviridae family and are known to cause emerging zoonotic diseases. These viruses have a high case fatality rate and are easily transmissible from person to person, which makes them capable of triggering outbreaks, including in non-endemic regions, and are also considered agents of bioterrorism. This review aims to improve clinical knowledge and the approach to suspected cases of FD. Improved surveillance and preparedness for potential global outbreaks are essential measures to effectively respond to these public health threats and to ensure that healthcare professionals are well-informed and prepared to deal with these diseases.

Resolution of egg binding is possible in most client-owned parrots when multiple treatment strategies are considered.
Of the 150 events that had complete follow-up, 109 (72.7%) resulted in a successful outcome. A successful outcome was observed in 44 of 133 events (33.1%) that were initially managed medically without resorting to additional treatment strategies, in 31 events (86.1%) managed with mechanical assistance, in 20 events (60.6%) managed surgically, and in 12 events (85.7%) managed with ovocentesis.

Investigating the relationship between canine training classes and post-adoption return rates in North American shelters
Of all the returned dogs, those who attended training were more likely to be returned for owner-related reasons (58.8?%), whereas dogs who did not attend training were more likely to be returned for animal-related reasons (78.9?%). While attending training classes at animal shelters may help to reduce behavioral returns, as shown by the shift in return reasons, they do not appear to reduce return rates significantly for the general shelter population.

Trust in veterinarians and association with vaccine information sources and vaccination status among dog and cat owners.
62.9% of dog and 61.2% of cat owners were classified as trusting their veterinarians. On average, dog owners consulted 2.50 sources about vaccine information; cat owners consulted 2.27 sources. Veterinarians were the most common primary sources of information for 85.4% of dog owners with high levels of trust, but only 62.6% of dog owners with lower levels. This was the case for 83.8% and 56.3% of cat owners.