Top 5 Goals for Management of Diabetes Mellitus

Clin Brief. Nov-Dec 2021;19(8):. 38 Refs

Thomas Schermerhorn¹

¹ College of Veterinary Medicine, Kansas State University, Manhattan, KS 66506, USA.

Author Abstract

Diabetic patients require multiple special considerations. See how your treatment strategies compare with this expert's top 5 management goals of treatment for dogs and cats.

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Efficacy, safety and interval from end of treatment to estrus in cats treated with an ultra-low dose megestrol acetate protocol for suppression of reproductive activity.
Twenty-eight queens were treated orally with 11.5 µg/kg/day of megestrol acetate (MA) for one to six months. MA suppressed reproductive function effectively in 27/28 queens. Transient mammary and uterine hyperplasia were detected in four (14 %) and three (11 %) queens, respectively, treated for more than four months, without associated clinical signs. Significant but reversible weight gain was observed in 85 % of the animals. The resumption of cyclicity occurred on average 6 weeks after the end of treatment but was influenced by the duration of treatment and seasonality.

Canine distemper outbreak and laryngeal paralysis in captive tigers (Panthera tigris).
All suspected and confirmed cases of CDV infections were significantly associated with laryngeal inflammation, which developed into paralysis in almost 50% of cases. Altogether, 50% of all tiger cases with chronic infection developed stridor at 314 days after virus infection. Therefore, laryngeal paralysis may result from CDV infection and degeneration, potentially affecting the peripheral and central nervous systems. This condition could pose a life-threatening risk to tigers.

Aseptic protocol breaches are common among veterinary students scrubbing, gowning, and gloving into surgery.
At least 1 aseptic protocol breach (APB) was noted in 46.3% of the 96 procedures observed. The most common mistakes noted were contact of the sterile towel onto nonsterile surfaces (17.7%), contact of the gown with nonsterile surfaces (17.7%), touching sterile objects with bare hands (12.5%), and improper scrubbing technique (17.4%).

Effective treatment with afoxolaner (NexGard) of Trixacarus caviae in a pet guinea pig.
The animal was treated with a single oral dose of 2.50 mg/kg afoxolaner, and the lesions, presence/absence of mites, and intensity of pruritus were evaluated periodically until 2 months post-treatment. A week after the medication, the lesions were milder, but pruritus was still present and was attributed to the healing process. Further examinations showed significant improvement with the complete remission of clinical signs and no mites at the microscopic examination after 4 weeks.

Litter box size and litter type preference and their associated behavioral changes in cats.
Our findings indicated that cats preferred litter boxes measuring ≥50 cm as well as clumping clay litter. Moreover, a comfortable litter environment combining these two elements promoted normal urination behavior while improving house-soiling (both urination and defecation).