Top 5 Breed-Specific Considerations to Avoid Adverse Drug Effects

Clin Brief. Jul-Aug 2021;19(5):. 27 Refs

Katrina Mealey¹, Michael H Court

¹ Veterinary Clinical Sciences, College of Veterinary Medicine, Washington State University, Pullman, WA 99164-7010, USA.

Author Abstract

Certain canine breeds known to harbor certain gene mutations and deficiencies may experience adverse drug effects. Genotyping and testing for these mutations can help identify at-risk dogs and minimize drug reactions.

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Upper and lower respiratory airway complaints among female veterinary staff.
Atopy was seen in 31% of the 109 female participants. Symptoms of rhinoconjunctivitis were the most frequent complaints (n = 92; 84%). Symptoms of upper and lower airways were highly correlated and an asthma diagnosis was confirmed in 11% of participants. Modelling revealed that sensitization against cats/dogs was a significant risk factor for respiratory symptoms of upper [odds ratio (OR) 4.61] and lower airways (OR 5.14), physician-confirmed rhinoconjunctivitis (OR 13.43), and asthma (OR 9.02) in assistant staff of small-animal practices.

Dentigerous cysts with exostosis of the temporal bone in horses – A new variant diagnosed by computed tomography
The dentigerous cyst or temporal teratoma in horses is a well-known congenital malformation that occurs in the temporal region and usually contains dental tissue. This case report describes two horses with a previously unreported variant of the dentigerous cyst associated with an exostosis arising from the temporal bone.

Enteral & Parenteral Nutrition in the Intensive Care Unit
Continual reassessment can help determine when to transition the patient from assisted feeding to voluntary consumption of food. Nutritional support should only be discontinued when the patient can consume ˜75% of their RER without support. In patients receiving parenteral nutrition, the transition to enteral nutrition should occur over at least 12 to 24 hours, depending on tolerance of enteral nutrition.

How Serious Are Health-Related Welfare Problems in Unowned Unsocialised Domestic Cats? A Study from Denmark Based on 598 Necropsies.
More than 83% of the cats had no major finding, and 54% had no finding indicating a welfare issue at all. More than 83% of the cats had a body condition within normal range. Only 0.3% were emaciated. The most common finding was infestation with ectoparasites, with 15.9% infected with lice, 12.3% with fleas, 4.7% with ticks, and 6.7% with ear mites. FIV and FeLV were detected in 9.2% and 1.2% of the cases, respectively.

Validation of a flash glucose monitoring system in outpatient diabetic cats.
Paired interstitial glucose and automated biochemistry analyzer glucose concentrations (139 samples) had excellent correlation as did interstitial glucose and point-of-care glucometer glucose concentrations (142 samples). Sensor failure or displacement were recorded for 12/15 (80%) sensor placements. Median time of sensor activity was 7 days (range, 2-13 days).