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ABSTRACT OF THE WEEK

Clinician's brief
Volume 19 | Issue 5 (Jul-Aug 2021)

Top 5 Breed-Specific Considerations to Avoid Adverse Drug Effects

Clin Brief. Jul-Aug 2021;19(5):. 27 Refs
Katrina Mealey1, Michael H Court
1 Veterinary Clinical Sciences, College of Veterinary Medicine, Washington State University, Pullman, WA 99164-7010, USA.

Author Abstract

Certain canine breeds known to harbor certain gene mutations and deficiencies may experience adverse drug effects. Genotyping and testing for these mutations can help identify at-risk dogs and minimize drug reactions.

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Archives Highlights:
The relationship between radiographic disc calcification score and FGF4L2 genotype in dachshunds.
Most dachshunds with 1 FGF4L2 copy have radiographic disc calcification scores that are associated with substantially lower risk of symptomatic disc disease. Radiographic disc calcification scores are similar in dachshunds with 0 and 1 FGF4L2 copies. Given the high allele frequency of FGF4L2, breeding to produce progeny with 1 FGF4L2 copy is expected to be a more achievable short-term goal for dachshund spinal health breeding programs than breeding for 0 copies. It is recommended that both K-n and FGF4L2 genotype status be considered when choosing dachshund breeding stock.
The Ideal Canine Companion: Re-Exploring Australian Perspectives on Ideal Characteristics for Companion Dogs.
The ideal dog was characterised as medium-sized, with a short- low- or non-shedding coat, and acquired as a puppy from a shelter/rescue. Desired traits included being affectionate, healthy, non-aggressive, safe with children, housetrained, non-destructive when alone, and not prone to escaping.
Owner satisfaction and prognosis for return to work after pancarpal arthrodesis in working dogs in the United Kingdom: a retrospective study (2011-2020).
50% (5/10) owners stated their dog could perform normal duties; 4/10 (40%) could perform most duties with some allowances. 80% (8/10) owners rated the level of post-operative lameness as unaffected with a normal gait. 90% (9/10) owners were either very satisfied or satisfied with the outcome of the procedure, and 90% owners stated the financial investment was worthwhile.
'Transmission Tracker - Dirofilaria'- a public dashboard to assess in real-time the temperature-bounded transmissibility of canine heartworm across Australia.
'Transmission Tracker - Dirofilaria' processes near real-time temperature records across Australia and allows users to enquire about historical and current weather suitability for canine heartworm transmission at any Australian postcode of their interest. This information allows veterinarians to access when, and for how long, heartworm may be transmitted at a specific location, assess the associated risk of infection, and advise on a patient-dependent dirofilariosis prevention plan for their canine patients and guardians.
Development of a dog owner caregiving style scale (Lincoln Owner Caregiving Questionnaire, LOCQ) and its relationship with behaviour problems in dogs
Compared to owners of dogs without behaviour problems, owners with high scores for the Disorganised caregiving style predicted dogs with separation related problems or with more than one behaviour problem, owners with high Avoidant caregiving style scores predicted dogs with Fear, and owners with high scores for both Disorganised and Avoidant caregiving styles predicted dogs with Aggressivity problems.

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