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ABSTRACT OF THE WEEK

Clinician's brief
Volume 19 | Issue 5 (Jul-Aug 2021)

Top 5 Breed-Specific Considerations to Avoid Adverse Drug Effects

Clin Brief. Jul-Aug 2021;19(5):. 27 Refs
Katrina Mealey1, Michael H Court
1 Veterinary Clinical Sciences, College of Veterinary Medicine, Washington State University, Pullman, WA 99164-7010, USA.

Author Abstract

Certain canine breeds known to harbor certain gene mutations and deficiencies may experience adverse drug effects. Genotyping and testing for these mutations can help identify at-risk dogs and minimize drug reactions.

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Archives Highlights:
The Most Common Environmental Risk Factors for Equine Asthma-A Narrative Review.
The symptoms of equine asthma are typical of respiratory inflammations, and they include coughing, nasal discharge, and breathing difficulty even at rest in horses with severe asthma. BALF and tracheal wash analyses are the most popular methods of diagnosing equine asthma. Inadequate housing conditions undoubtedly increase the risk of asthma.
Prevalence of discospondylitis and association with congenital vertebral body malformations in English and French bulldogs.
The prevalence of discospondylitis was 3.4 (1.6-6.7) times higher in French bulldogs and 4.3 (1.7-9.8) times higher in English bulldogs, compared with the overall hospital cohort. One or more vertebral malformations were present in 12 French bulldogs (92.3%), 6 English bulldogs (75.0%), and 1 "other" breed dog (1.1%). Discospondylitis was diagnosed adjacent to congenital vertebral body malformations in 12 (80%) intervertebral discs in French bulldogs and 5 (50%) intervertebral discs in English bulldogs.
Choose Your Own Adventure: Using Twine for Gamified Interactive Learning in Veterinary Anaesthesia.
Five interactive clinical cases were developed using Twine, simulating realistic anaesthesia scenarios with decision points and gamified elements, such as scoring systems and resource management. Feedback was highly positive; 90.8% found it effective for training, and 97.0% agreed it improved knowledge. User-friendliness was rated as "easy" or "very easy" by 94.6%. Regarding overall satisfaction, 96.7% of students described the workshop as "good" or "excellent".
Effects of intranasal maropitant on clinical signs of naturally acquired upper respiratory disease in shelter cats.
There was no significant difference in clinical improvement score between the maropitant treatment and control groups for conjunctivitis, blepharospasm, ocular discharge, nasal discharge, or total disease severity after 7 days.
How to plan and provide general anesthesia for a troop of 98 hamadryas baboons (Papio hamadryas) for contraceptive and preventative health interventions.
A group of 12 veterinarians, 2 zookeepers, and 6 volunteers anesthetized all animals within 2 days. The baboons were orally premedicated with midazolam (0.1 to 0.5 mg/kg) and anesthetized with medetomidine (40 to 60 µg/kg, IM) and ketamine (2 to 4 mg/kg, IM); isoflurane at rates of 1.5% to 2% was used for maintaining anesthesia if necessary. For population management, the animals received a contraceptive implant (adult females), orchiectomy (young males), or vasectomy (breeding males).

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