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ABSTRACT OF THE WEEK

Clinician's brief
Volume 19 | Issue 5 (Jul-Aug 2021)

Top 5 Breed-Specific Considerations to Avoid Adverse Drug Effects

Clin Brief. Jul-Aug 2021;19(5):. 27 Refs
Katrina Mealey1, Michael H Court
1 Veterinary Clinical Sciences, College of Veterinary Medicine, Washington State University, Pullman, WA 99164-7010, USA.

Author Abstract

Certain canine breeds known to harbor certain gene mutations and deficiencies may experience adverse drug effects. Genotyping and testing for these mutations can help identify at-risk dogs and minimize drug reactions.

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Archives Highlights:
Choose Your Own Adventure: Using Twine for Gamified Interactive Learning in Veterinary Anaesthesia.
Five interactive clinical cases were developed using Twine, simulating realistic anaesthesia scenarios with decision points and gamified elements, such as scoring systems and resource management. Feedback was highly positive; 90.8% found it effective for training, and 97.0% agreed it improved knowledge. User-friendliness was rated as "easy" or "very easy" by 94.6%. Regarding overall satisfaction, 96.7% of students described the workshop as "good" or "excellent".
Recovery of ambulation in small, nonbrachycephalic dogs after conservative management of acute thoracolumbar disk extrusion.
Forty-nine of fifty-one (96%) of deep pain-positive and 10/21 (48%) of deep pain-negative dogs recovered ambulation within the 12-week period. The median time to ambulation was 11 and 25 days for deep pain-positive and -negative dogs, respectively. Reduction in spinal cord compression varied among individuals from minimal to complete and apparently was unrelated to the recovery of ambulation.
Guide for nonswine practitioners to enhance swine disease diagnoses.
This review aims to help clinicians across the country that may not have an in-depth experience in swine medicine become more familiar with both common and novel pathogens, formulate a differential diagnosis based on the age of the animals and affected system (eg, respiratory, systemic, nervous, and enteric), select proper samples and laboratory testing, and interpret laboratory data to achieve a disease diagnosis in porcine patients.
Adjuvant Chemotherapy Is Associated With Prolonged Survival Time in Small-Breed Dogs Undergoing Amputation for Appendicular Osteosarcoma.
The median time to distant progression for all dogs was 265 days, with no significant difference between treatment groups. The median overall survival for all dogs was 270 days, and it was significantly different between amputated dogs (150 days) and those also receiving adjuvant chemotherapy (353 days). In our cohort, osteosarcoma in small breeds behaved as aggressive as in large breeds.
Mass rabies exposure of veterinary health care workers in Germany: Management, immune response, and tolerability of post exposure-prophylaxis.
In 2008, Germany was declared free from terrestrial rabies by the WOAH. However, illegal pet imports can still lead to rabies exposure, as seen in the 2021 case of a rabid puppy illegally imported to Germany, resulting in a mass exposure (39 veterinary clinic staff) incident.

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