VSPN AOW : Disappearance of signs of... |
Disappearance of signs of heat and induction of ovulation in oestrous queens with gonadorelin: a clinical study.J Feline Med Surg. April 2021;23(4):344-350.1 Department of Animal Medicine, Production and Health, University of Padova, Padova, Italy.; 2 Veterinary Clinic, Aulla, Italy.; 3 Department of Veterinary Medicine, University of Pisa, Pisa, Italy.; 4 Department of Animal Medicine, Production and Health, University of Padova, Padova, Italy.
AbstractOBJECTIVES:The objective of this study was to assess the efficacy of a single intramuscular administration of gonadorelin to induce ovulation in queens in oestrus.
METHODS:Twenty-seven queens presented in oestrus for elective ovariectomy were divided into a treatment (n = 19) and a placebo (n = 8) group. Treated queens received a 50 µg dose of gonadorelin, while placebo-treated queens were injected intramuscularly (IM) with an equal amount of saline solution. All treatments were performed between the second and fourth days of heat.
RESULTS:Two days later, signs of behavioural heat had disappeared in all gonadorelin-treated queens, while 5/8 placebo-treated queens were still in heat. Following ovariectomy, performed 4 days after drug administration, the ovaries of each queen were evaluated histologically and the number of corpora lutea were counted. Sixteen of 19 (84%) gonadorelin-treated queens had ovulated and developed five (range 2-9) corpora lutea, while 3/8 (37%) placebo-treated queens had ovulated and developed five (range 3-6) corpora lutea.
CONCLUSIONS AND RELEVANCE:This is the first study to document the efficacy of a 50 µg/cat gonadorelin dose to induce ovulation in oestrous queens when administered IM on days 2-4 following the onset of oestrus.
Keywords
Ovulation*;
behavioural oestrus*;
corpora lutea*;
gonadorelin*;
Keywords
Ovulation;
behavioural oestrus;
corpora lutea;
gonadorelin;
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VSPN AOW : Disappearance of signs of... |
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