2020 Miller Trust Grant Awards
Published: January 30, 2023
Winn Feline Foundation

EveryCat Health Foundation
(formerly Winn Feline Health Foundation)

George Sydney and Phyllis Redman Miller Trust
Funded for a total of $164,499

High-Density Cat DNA Array Genome-Wide Association Studies. $38,198
Investigator: Leslie A. Lyons; University of Missouri-Columbia MT20-013, MTW20-013 (combined funding from the Miller Trust and the Andorra Fund with sponsorship from the Southern California Burmese Cat Club)
This project will focus on the condition of amyloidosis in Oriental/Siamese cats to narrow down the region(s) of the genome associated with this disease. 

Feline congenital primary hypothyroidism: Establishing normal reference intervals and treatment guidelines. $35,000
Investigators: Karen Vernau, Stanley Marks, Sean Heulsebosch, and William Vernau, University of California-Davis MT20-011
The goal is to establish normal reference intervals for thyroid hormone in kittens at 4 and 8 weeks of age, and to establish treatment guidelines for hypothyroidism in kittens.

Development of improved cell culture systems for feline coronavirus and FIP vaccine development. $17,500
Investigators: Gary Whittaker, Cornell University; Susan Baker, Loyola University MT20-008
With this study, researchers hypothesize that FIPV type I enters cells, including macrophages, through the ACE2 receptor, as has been determined with SARS-CoV-2 in people. They propose to show that ACE2 and host proteases are key drivers of viral pathogenesis in FIP.

Effects of dual antithrombotic therapy using rivaroxaban and clopidrogrel on platelet function and coagulation parameters in cats. $18,801
Investigators: Joshua Stern and Ronald Hak Long Li; University of California - Davis MT20-007
This study proposes to compare the safety and effectiveness of single-agent therapy of clopidogrel or rivaroxaban to the combined dual therapy with both drugs.

Characterization of myeloid cell phenotypes and frequencies in feline cancers and infectious disease. $20,000
Investigator: Ellen Sparger, University of California - Davis MT20-004
This study will develop and validate a panel that measures these cell types in healthy cats and in samples from cats with a particular cancer, feline oral squamous cell carcinoma. Later, this panel can be used to investigate other cancers and infectious disease like feline infectious peritonitis (FIP).

Impact of iron deficiency on short-term response to treatment in cats with inflammatory bowel disease. $35,000
Investigators: Maria Jugan, Kansas State University; Catherine Langston, The Ohio State University MT20-02 
The study will investigate whether cats with iron deficiency have a decreased response to standard-of-care treatment for GI disease, results would expand treatment options for cats affected by long-standing GI disease.