Haematology, Urinalysis, and Pathomorphological Findings in Indian Leopards (Panthera pardus) with Glomerulonephritis
2018 Joint EAZWV/AAZV/Leibniz-IZW Conference
Kafil Hussain1, PhD; Shafiqur Rehman2, PhD; J.S. Soodan3, PhD; M.M.S. Zama4, PhD; S.K. Gupta5, PhD
1Associate Professor , Division of Veterinary Medicine, FVSc & AH, SKUAST-J, R S Pura, Jammu (J&K), India; 2Assistant Professor, Division of Veterinary Pathology, FVSc & AH, SKUAST-J, R S Pura, Jammu (J&K), India; 3Professor and Head, Division of Teaching and Veterinary Clinical Complex (TVCC) ,Faculty of Veterinary Science and Animal Husbandry, Sher-e-Kashmir University of Agricultural Sciences and Technology of Jammu (J&K), R S Pura, Jammu, India; 4Dean, Faculty of Veterinary Science and Animal Husbandry, Sher-e-Kashmir University of Agricultural Sciences and Technology of Jammu (J&K), R S Pura, Jammu, India; 5Head, Division of Veterinary Medicine, FVSc & AH, SKUAST-J, R S Pura, Jammu (J&K), India
The present study describes the haematology, urinalysis, and pathomorphological findings in Indian leopards (Panthera pardus) affected with glomerulonephritis at Manda Zoo of Jammu (Jammu and Kashmir) of India. Two leopards (male and female) were lethargic, had increased thirst, and blood in urine with lack of interest in their surroundings. Haematuria was the consistent feature in both the cases. The complete blood count of the surviving female leopard showed leukocytosis. Serum biochemistry revealed azotemia, hyperkalemia, hypoalbuminemia, and a mild increase in serum aspartate aminotransferase (AST) concentration. Urinalysis showed increased numbers of red and white blood cells, moderate albuminuria, and mild glucosuria. These signs supported the diagnosis of nephritis. Both leopards were treated with intensive intravenous fluid therapy and antibiotics for 3 days. The therapeutic objective was to normalize fluid balance, solve hemodynamic problems, and promote urine production. The female leopard clinically improved within 2 days of treatment and fully recovered. The male leopard died during the treatment and a complete necropsy with histopathology was performed. Grossly, the kidneys showed a rough, uneven cortex with a firmly adhered capsule. On histopathological examination, the kidneys showed severe degeneration and swelling of epithelial cells within the proximal convoluted tubules which completely occluded the lumen with hypercellularity of glomerular tufts causing loss of urinary space.
The authors thanks to Chief Wildlife Warden (J&K) and associated staff of Manda Zoo at Jammu for providing necessary facilities for the treatment of the leopards.