A List of Available Canine and Feline Genetic Tests
Tufts' Canine and Feline Breeding and Genetics Conference, 2007
Jerold S. Bell, DVM
Tufts Cummings School of Veterinary Medicine
North Grafton, MA, USA

Available Genetic Tests for Breed Specific Canine and Feline Genetic Disorders

Disorder

Breeds

Type of test

Test facility

Canine Leukocyte Adhesion Deficiency (CLAD)

Irish Red & White Setter
Irish Setter

Direct

Optigen
Animal Health Trust

Cataract, Juvenile (Early Onset Hereditary Cataract--EHD)

Boston Terrier
French Bulldog
Staffordshire Bull Terrier

Direct

Animal Health Trust

Ceroid lipofuscinosis

Border Collie

Direct

Animal Health Trust
Optigen

Ceroid lipofuscinosis

American Bulldog
Dachshund
English Setter

Direct

U Missouri

Coat Color and Nose Color Variation

Australian Shepherd
Border Collie
Brittany
Belgian Shepherd
Cardigan Welsh Corgi
Collie (Rough, Smooth)
Cocker Spaniel
Curly-Coated Retriever
Dachshund
Dalmatian
Doberman Pinscher
English Cocker Spaniel
English Setter
English Springer Spaniel
Field Spaniel
Flat-coated Retriever
French Bulldog
German Shepherd
German Longhaired Pointer
German Shorthaired Pointer
German Wirehaired Pointer
Great Dane
Greyhound
Groenendael
Labrador Retriever
Laekenois
Large Munsterlander
Lowchen
Malinois
Newfoundland
Pointer
Pomeranian
Poodle
Portuguese Water Dog
Pudelpointer
Shetland Sheepdog
Staffordshire Bull Terrier
Tervuren
Whippet
Wirehaired Pointing Griffon

Direct

HealthGene

Coat Color Gene Variations

Alaskan Klee Kai
American Cocker Spaniel
Australian Cattle Dog
Border Collie
Curly Coated Retriever
Dalmatian
Doberman Pinscher
English Cocker Spaniel
English Springer Spaniel
Flat Coated Retriever
Gordon Setter
Labrador Retriever
Newfoundland
Pointer
Poodle
Schipperke
Scottish Terrier
Stumpy Tail Cattle Dog

Direct

VetGen

Coat Length (FGF5)

Weimaraner

Direct

Animal Health Trust

Cobalamin Malabsorption (Methylmalonic Aciduria)

Australian Shepherd
Giant Schnauzer

Direct

PennGen

Cobalamin Malabsorption
(Methylmalonic Aciduria)

Beagle
Border Collie
DSH
Shar Pei

Phenotypic

PennGen

Collie Eye Anomaly
(Choroidal Hypoplasia)

Australian Shepherd
Border Collie
Lancashire Heeler
Nova Scotia Duck Tolling Retriever
Rough Coated Collie
Shetland Sheepdog
Smooth Coated Collie
Whippet. Longhair

Direct

Optigen

Cone (Retinal) Degeneration

German Shorthaired Pointer

Direct

Optigen

Congenital Hypothyroidism with Goiter (CHG)

Rat Terrier
Toy Fox Terrier

Direct

Michigan State University--Fyfe Lab.
PennGen

Congenital Stationary Night Blindness (RPE65-CSNB)

Briard

Direct

Optigen
Animal Health Trust

Copper Toxicosis

Bedlington Terrier

Direct

VetGen
Animal Health Trust

Cyclic Neutropenia (Grey Collie Syndrome)

Smooth Coated Collie
Rough Coated Collie

Direct

HealthGene

Cystinuria

Newfoundland
Labrador Retriever

Direct

Optigen (Newf only)
PennGen
VetGen (Newf only)

Degenerative Myelopathy (DM)

German Shepherd Dog (FLASH test)
Boxer (RAPD)
Pembroke Welsh Corgis (RAPD)
Rhodesian Ridgeback (RAPD)

Direct (susceptibility loci)

U-Fla--Neuro Service

Factor VII Deficiency

Alaskan Klee Kai
Beagle
Scottish Deerhound

Direct

PennGen

Factor IX Deficiency
(Hemophilia B)

Airedale Terrier
Bull Terrier
German Wirehaired Pointer Labrador Retriever
Lhasa Apso

Direct

Cornell Univ. Comparative Coag. Lab (GWP)
HealthGene (Others)

Factor XI Deficiency

Kerry Blue Terrier

Direct

PennGen

Fanconi Syndrome

Basenji

Linked Marker

U-Missouri

Fanconi Syndrome

Basenji
Norwegian Elkhound

Phenotypic

PennGen

Fucosidosis

English Springer Spaniel

Direct

PennGen
Animal Health Trust

Glanzmann's Thrombasthenia (Type I)

Great Pyrenees
Otterhound

Direct

Auburn Univ.--Boudreaux Lab.

Globoid cell leukodystrophy

Cairn terrier
West Highland White Terrier

Direct

Jefferson Medical Coll.

Glycogenosis (GSD) Type IIIa

Curly Coated Retriever

Direct

Michigan State University--Fyfe Lab.

Glycogenosis (GSD) Type IV

Norwegian Forest Cat

Direct

PennGen

GM1-Gangliosidosis

Portuguese Water Dog

Direct

New York University Neurogenetics Lab

Hypertrophic Cardiomyopathy

Maine Coon Cat
Ragdoll

Direct

Washington State U--Meurs Lab

Ivermectin Sensitivity
(MDR1)

Australian Shepherd
Collie
Old English Sheepdog
Shetland Sheepdog
Other breeds

Direct

Washington State U--Pharm Lab

L-2-HGA (L-2-hydroxyglutaric aciduria)

Staffordshire Bull Terrier

Direct

Animal Health Trust

Mannosidosis

DSH
Persian

Direct

PennGen

Merle Gene (SILV)

Australian Shepherds
Beauceron Sheepdog
Border Collie
Cardigan Welsh Corgi
Catahoula Leopard Dog
Chihuahua
Cocker Spaniel
Collie
Dachshund
Great Danes
Norwegian Hound
Pitt Bull
Pomeranian
Pyrenean Shepherd
Shetland Sheepdogs

Direct

GenMARK

Mucolipidosis II (I-Cell Disease)

DSH

Direct

PennGen

Mucopolysaccharidosis (MPS)

DSH
German Shepherd Dog
Miniature Pinscher
Miniature Schnauzer
Schipperke
Siamese

Direct

PennGen

Muscular Myopathy (Centronuclear myopathy)

Labrador Retriever

Direct

Alfort School of Veterinary Medicine, France

Myotonia Congenital

Miniature Schnauzer

Direct

Optigen
PennGen

Narcolepsy

Dachshund Doberman Pinscher Labrador Retriever

Direct

Optigen

Neonatal Encephalopathy

Standard Poodle

Direct

U Missouri

Nephropathy (Hereditary N., Familial N.)

English Cocker Spaniels

Direct

Optigen

Phosphofructokinase Deficiency (PFK)

American Cocker Spaniel
English Springer Spaniel

Direct

Optigen
PennGen
VetGen
Animal Health Trust (ESS)

Polycystic Kidney Disease (PKD)

American Shorthair
Himalayan
Persian
Scottish Fold

Direct

UC-Davis--Lyons Lab.
Animal Health Trust

Primary Hyperparathyroidism

Keeshond

Linkage

Cornell--Goldstein Lab

Progressive Retinal Atrophy (cord1)

Dachshund, Miniature Longhaired
English Springer Spaniel

Direct

Animal Health Trust
U-Missouri

Progressive Retinal Atrophy--Dominant

Bullmastiff
(English) Mastiff

Direct

Optigen

Progressive Retinal Atrophy (prcd)

American Cocker Spaniel
American Eskimo Dog
Australian Cattle Dog
Australian Shepherd
Chesapeake Bay Retriever
Chinese Crested
Cockapoo
English Cocker Spaniel
Entelbucher Mountain Dog
Finnish Lapphund
Golden Retriever
Kuvasz
Labradoodle
Labrador Retriever
Lapponian Herder
Nova Scotia Duck Trolling Retriever
Poodle; Miniature & Toy
Portuguese Water Dog
Spanish Water Dog
Stumpy Tail Cattle Dog
Swedish Lapphund

Direct

Optigen

Progressive Retinal Atrophy (rcd1)

Irish Red & White Setter
Irish Setter
Sloughi (rcd1a)

Direct

Optigen
Animal Health Trust
VetGen (Irish Setter)

Progressive Retinal Atrophy (rcd3)

Cardigan Welsh Corgi

Direct

Michigan State Univ.--
Peterson-Jones Lab.
Optigen
VetGen

Progressive Retinal Atrophy--Type A

Miniature Schnauzer

Direct

Optigen

Progressive Retinal Atrophy--X-Linked

Samoyed
Siberian Husky

Direct

Optigen

Pyruvate Dehydrogenase Phosphatase Deficiency
(PDH or PDP1)

Clumber Spaniel
Sussex Spaniel

Direct

U-Missouri
Animal Health Trust

Pyruvate Kinase Deficiency (PK)

Abyssinian
American Eskimo Dog Basenji
Beagle
Cairn Terrier
Chihuahua
Dachshund
DSH
Somali
West Highland White Terrier

Direct

Optigen (Basenji)
PennGen (All)
VetGen (Basenji)
Animal Health Trust (Westies)

Renal Dysplasia

Lhasa Apso
Shih Tzu
Soft Coated Wheaton Terrier

Linkage

VetGen

Retinal Dysplasia--Canine Multi-focal Retinopathy (CMR)

Bullmastiff
Coton de Tulear
Dogue de Bordeaux
Great Pyrenees
Mastiff (English & French)

Direct

Optigen

Severe Combined Immunodeficiency (SCID)

Bassett Hound
Cardigan Welsh Corgi
Pembroke Welsh Corgi

Direct

PennGen

Spinal Muscular Atrophy

Maine Coon Cat

Direct

Michigan State University--Fyfe Lab.

Thrombopathia

Bassett Hound
Landseer
Spitz

Direct

Auburn Univ.--Boudreaux Lab.

Trapped Neutrophil Syndrome (TNS)

Border Collie

Linkage

Univ. New South Wales

Von Willebrand's Disease

Bernese Mountain Dog
Doberman Pinscher
Drentsche Patrijshound
German Pinscher
Kerry Blue Terrier
Manchester Terrier
Papillion
Pembroke Welsh Corgi
Poodle
Scottish Terrier
Shetland Sheepdog

Direct

VetGen

Von Willebrand's Disease

Irish Red and White Setters

Direct

Animal Health Trust

URLs and Emails

1.  Alfort School of Veterinary Medicine, France: http://www.labradorcnm.com/

2.  Animal Health Trust (England): http://www.aht.org.uk/sci_diag_disc_genetics_dna.html#canine

3.  Auburn Univ.--Boudreaux Lab: http://www.vetmed.auburn.edu/index.pl/boudreaux_mk (334-844-2692)

4.  Cornell--Goldstein Lab: http://www.vet.cornell.edu/labs/goldstein/ (607-253-4480)

5.  Cornell Univ. Comparative Coagulation Lab: http://www.diaglab.vet.cornell.edu/coag/test/hemopwh.asp (607-275-0622)

6.  GenMARK: http://www.genmarkag.com/home_companion.php (877-766-3446)

7.  HealthGene: www.healthgene.com (877-371-1551)

8.  Jefferson Medical College: David.wenger@mail.tju.edu (215-955-1666)

9.  Michigan State University-Peterson-Jones Lab.: http://www.cardigancorgis.com/ (517-353-3278)

10.  Michigan State University-Fyfe Lab.: http://mmg.msu.edu/faculty/fyfe.htm (517-355-6463x1559)

11.  New York University Neurogenetics Laboratory: http://www.pwdca.org/ (212 263-2943)

12.  Optigen: www.optigen.com (607-257-0301)

13.  PennGen: www.vet.upenn.edu/penngen (215-898-8894)

14.  UC-Davis--Lyons Lab.: http://www.vgl.ucdavis.edu/service/cat/PKD.html (530-752-2211)

15.  U Missouri--Johnson Lab: http://www.caninegeneticdiseases.net/ (573)-884-3712)

16.  Univ. New South Wales--Wilton Lab: a.wilton@unsw.edu.au

17.  U-Fla--Neuro Service: http://neuro.vetmed.ufl.edu/dm_flash_test_web/index.html (352-392-4700 x4700)

18.  VetGen: www.vetgen.com (800-483-8436)

19.  Washington State U--Meurs Lab: http://www.vetmed.wsu.edu/deptsVCGL/ (509-335-6038)

20.  Washington State U--Pharm Lab: http://www.vetmed.wsu.edu/announcements/ivermectin/ownerInfo.asp (509-335-3745)

Speaker Information
(click the speaker's name to view other papers and abstracts submitted by this speaker)

Jerold S. Bell, DVM
Tufts Cummings School of Veterinary Medicine
North Grafton, MA


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