Occurrence of Feline Immunodeficiency Virus in Naturally Infected Domestic Cats
WSAVA 2002 Congress
*Valéria Maria Lara, João Pessoa Araújo Jr, Sueli Akemi Taniwaki, Carlos Alberto Magalhães Lopes
*Faculdade de Medicina Veterinária e Zootecnia-Universidade Estadual Paulista-UNESP
Botucatu, São Paulo, BR
vallara@uol.com.br

OBJECTIVES

Feline immunodeficiency virus (FIV) is the main retrovirus that infects domestic cats. The infection, as observed in human immunodeficiency virus, is characterized by a long period without signs of disease, followed by increased susceptibility to opportunistic infections. FIV has been detected all over the world. In Europe, its prevalence ranges from 2% (in Germany and The Netherlands) to 33% (United Kingdom). In America, this infection percentage varies from 1-16%. Japan has a very high prevalence of FIV (44%). An explanation for the differences in infection rates may be the different health status of the cats. Epidemiological investigations show that FIV transmission is influenced by cat behavior. The goal of this work was to evaluate FIV occurrence in naturally infected-domestic cats.

MATERIALS

489 blood samples were collected from domestic cats in several cities of São Paulo State, Brazil, in a radius approximately of 200 Km, since October 2000 till December 2001. DNA was extracted using "GFX genomic Blood DNA purification kit" (APBiotech, Inc), as recommended by manufacturer. After extraction, 329-base pair were amplified by nested PCR, according to Hohdatsu et al.(1998). PCR products were submitted to electrophoresis in 2% agarose gel, stained with ethidium bromide and visualized by UV transillumination at 312 nm.

RESULTS

Among 489 samples, 14,5% (71/489) were positive, being 74,6% males and 25,3% females. Only 30,9% of the positive cases showed immunosuppression symptoms.

CONCLUSION

These results confirm FIV occurrence in domestic cats in São Paulo State, Brazil. The rate of 14,5% FIV infection is quite near from that found in USA. The remarkable difference found in the proportion between males and females infected by FIV in our work and also in those reported by other researchers could be explained by the virus transmission mechanism (bite and infective saliva) and by male cat's behavior, constantly fighting with others males for defense of their territory.

Speaker Information
(click the speaker's name to view other papers and abstracts submitted by this speaker)

Carlos Alberto Magalhães Lopes
Instituto de Biociências-UNESP

João Pessoa Araújo Jr
Instituto de Biociências-UNESP

Sueli Akemi Taniwaki
Faculdade de Medicina Veterinária e Zootecnia-UNESP

Maria Lara Valéria
Faculdade de Medicina Veterinária e Zootecnia-Universidade Estadual Paulista-UNESP
Distrito de Rubião Júnior, S/N
Botucatu, São Paulo 18618-000 BR


MAIN : : FIV in Naturally Infected Domestic Cats
Powered By VIN

Friendly Reminder to Our Colleagues: Use of VIN content is limited to personal reference by VIN members. No portion of any VIN content may be copied or distributed without the expressed written permission of VIN.

Clinicians are reminded that you are ultimately responsible for the care of your patients. Any content that concerns treatment of your cases should be deemed recommendations by colleagues for you to consider in your case management decisions. Dosages should be confirmed prior to dispensing medications unfamiliar to you. To better understand the origins and logic behind these policies, and to discuss them with your colleagues, click here.

Images posted by VIN community members and displayed via VIN should not be considered of diagnostic quality and the ultimate interpretation of the images lies with the attending clinician. Suggestions, discussions and interpretation related to posted images are only that -- suggestions and recommendations which may be based upon less than diagnostic quality information.

CONTACT US

777 W. Covell Blvd., Davis, CA 95616

vingram@vin.com

PHONE

  • Toll Free: 800-700-4636
  • From UK: 01-45-222-6154
  • From anywhere: (1)-530-756-4881
  • From Australia: 02-6145-2357
SAID=27