

Attend ACVIM Student Rounds
The next ACVIM Student Rounds session takes place this Wednesday at 8 pm ET. Join Jeff Toll, VMD, DACVIM, and Adam Birkenheuer, DVM, PhD, DACVIM, for Becoming A Well-Rounded Veterinary Clinical Scientist. Follow the link on the Rounds page to attend this session.
Collect the Best Derm Sample!
Simple in-clinic procedures help us diagnose or rule-out skin disorders. Sample collection and sample handling are critical steps essential to an accurate diagnosis whether analysis of the sample will take place in-house or via an outside diagnostic service. Common Dermatological Diagnostic Tests -- a VIN Medical FAQ -- provides guidelines for collecting samples that are likely to be of diagnostic quality when working up skin diseases. Check out the rest of the VIN Medical FAQs!
Featured Book:
Veterinary Practice Consultants Signature Series Monographs, Fundamental Money Management for the Veterinary Practice - Catanzaro, 2003, is now available in the VIN Bookstore!
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Pharmacokinetics of cefovecin in cats
The pharmacokinetics of the novel cephalosporin cefovecin were investigated in a series of in vivo, ex vivo and in vitro studies following administration to adult cats at 8 mg/kg bodyweight. Bioavailability and pharmacokinetic parameters were determined in a cross-over study after intravenous (i.v.) and subcutaneous (s.c.) injections. The slow elimination and long-lasting free concentrations in extracellular fluid are desirable pharmacokinetic attributes for an antimicrobial with a 14-day dosing interval.
Effects of subcutaneous methadone, morphine, buprenorphine or saline on thermal and pressure thresholds in cats
This study compared pressure and thermal thresholds after administration of three opioids in eight cats. Pressure stimulation was performed via a bracelet taped around the forearm. Three ball-bearings were advanced against the forearm by inflation of a modified blood pressure bladder. Thermal threshold was tested as previously reported using a heated probe held against the thorax. After baseline recordings, each cat received subcutaneous methadone 0.2 mg/kg, morphine 0.2 mg/kg, buprenorphine 0.02 mg/kg or saline 0.3 mL in a four period cross-over study. Morphine provided the best analgesia, and methadone appears a promising alternative. Buprenorphines limited effect was probably related to the subcutaneous route of administration. Previously, buprenorphine has produced much greater effects when given by other routes.
If control of Neospora caninum infection is technically feasible does it make economic sense?
Recent work on Neospora caninum, a protozoan parasite that causes abortions in dairy cattle, has focused on a number of different control options. Modelling has suggested the most effective options for control, but the present paper argues that the most effective option might not necessarily be optimal from an economic point of view. Decision trees, using published quantitative data, were constructed to choose between four different control strategies. The costs of these interventions, such as 'test and cull', therapeutic treatment with a pharmaceutical, vaccination, or "doing nothing" were compared.
Comparison of bovine in vivo bioavailability of two sulfamethazine oral boluses exhibiting different in vitro dissolution profiles
The current study was undertaken to determine whether an in vivo/in vitro correlation can be established for bovine sulfamethazine oral boluses and to acquire insight into the magnitude of changes in in vitro product performance that can occur before corresponding changes are seen in in vivo blood level profiles. Based upon the results of this investigation, it is concluded that marked changes in in vitro sulfamethazine bolus performance can be tolerated before resulting in altered in vivo blood level profiles. However, the data also suggest that rumenal absorption may occur for some compounds. Therefore the degree to which variation in product in vitro dissolution profiles can be tolerated may be compound specific.


When To Extract Teeth With Resorptive Lesions In A Dog?
There is some conflict concerning the care of canine resorption lesions. Most feel if the lesion does not penetrate into the oral cavity, then leave them alone until they do. Others feel the teeth should be proactively extracted.
The Power Of Nice: Treating Others With Kindness And Respect
Just as positive actions are like seeds, rude gestures and remarks are like germs -- you may not see the impact they have on you for a while, but they are there, silently infecting you and everyone around you. When you truly understand the full power of nice, you realize that by treating others with kindness, respect, and generosity, your actions get paid back in one way or another -- with interest.
Diagnostics And Differential Diagnoses For Low Urine Specific Gravity; In-House Urine Cultures, Supplies, And Equipment
I have just started doing in house urine culture. I bought a used incubator for about $175. It is not pretty but works fine.
What Is Your Mission Statement?
"We become what we think about." This is about the simplest description of the benefits of strategic planning (mission-vision-goals) that I've ever come across. If we think about something long enough and hard enough, we'll achieve it.
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Virtual Coffeehouse
Tuesday, February 27, 9:30 pm ET Is the weather getting to you? Stop by and tell us! This Week's Rounds Schedule -- use the Coffeehouse link to join the discussion.
Calling All Students -- ACVIM Student Rounds --
Special Day & Time: Wednesday, February 28, 8 pm ET Join Jeff Toll, VMD, DACVIM, and Adam Birkenheuer, DVM, PhD, DACVIM, for Becoming A Well-Rounded Veterinary Clinical Scientist. This Week's Rounds Schedule -- use the Rounds link to join the discussion.
Sunday Rounds
Sunday, March 4, 10 pm ET Join David Aucoin, DVM, DACVCP, for Case Management Of Enterococcus Infections. This Week's Rounds Schedule -- use the Rounds link to join the discussion.
Recent Rounds


Abstract Of The Week: The potential of oral vaccines for disease control in wildlife species
What's Your Diagnosis? * Ophthalmology Case: 8 * Case Archives
Associate - Updated and New: * Liver disease causes skin problems? Absolutely possible. See Hepatocutaneous syndrome. Explore the rest of the Associate!
Website Of The Week: Equine Color Genetics Information and more ...
Book Review of the Week: The Feline Patient You may purchase this book in the VIN store. Get More From VIN! * How Do I...Email Another VINner? * Read The "How To Use VIN" Tutorial * How Can I ... Learn Associate? * How Can I ... Become A Super-Duper VIN User?
eVetsites Tip of the Week: Type Fonts on eVetsites Should be Simple and Clear
Upcoming Conferences Looking to attend -- or contribute a paper to -- a veterinary conference? Check out the On The Road With VIN folder, or the Press Releases folder, to see what conferences are coming up and to visit their web sites! Links to information about upcoming conferences include: SAVMA, BSAVA, and NAVDF.
From the Boards:
* Zoonosis: Hepatitis E * Favorite VIN Quotes * Louse Control In Goats * Is A C-Reactive Protein Test Useful?


Organ System and ABVP Core Examination Review Module A
The Organ System and ABVP Core Examination Review course is divided into 3 modules. Each module provides a systematic review of the physiology & pathophysiology of the organ systems included in that section. You will be able to use the 3 modules of this course as a focused and comprehensive preparation tool for the ABVP Core Examination. Even if you aren't going to take the exam, the depth and breadth of this material will provide you with an up-to-date review of organ system pathophysiology. Module A (March 29 - May 24, 2007) includes the following topics: Neurology, Coagulation, Oncology, Immunology, Surgery, Anesthesia and Dentistry* Dates: March 29 - May 24, 2007 Real-time sessions: Thursdays: March 29, April 5, 12, 19, 26, May 3, 10, and 17; 9:30 - 11:30 pm ET CE Hours: 16 Course Coordinator: Katherine M. James, DVM, PhD Course Outline and Instructors: Coagulation and Oncology (2 weeks) -- Karri Meleo, DVM, DACVIM, DACVR and TBA Anesthesia -- TBA Dentistry -- Steve Holmstrom, DVM, DAVCD Immunology -- Robert M. Gogal Jr, DVM Surgery -- Bob Richardson, DVM and Joe Hauptman, DVM, MS, DACVS Neurology (2 weeks) -- Anne Katherman, DVM, DACVIM and William Thomas, DVM, MS, DACVIM (Neurology) Module B (June 14 - August 9, 2007) includes the following topics: Respiratory, Pharmacology, Infectious Disease, Dermatology, Fluids/Acid Base, Nephrology/Urology and Ophthalmology.* Module C (Aug 23 - Oct 25, 2007) includes the following topics: Cardiology, Endocrinology, Gastroenterology, Reproduction and Hematology/Chemistry.* *Topics subject to change between modules. Tuition: Member/$266, Non-Member/$373 by March 15, 2007; Member/$296, Non-Member/$414 after March 15, 2007 Register for all 3 ABVP Modules by the start date of Module A on March 29, 2007 and you will receive a discounted tuition rate of Member/$758, Non-Member/$1063. Required Textbook: None Recommended Textbooks: Will be listed when the course opens To find out more: Visit the Organ System and ABVP Modules course information pages: To register, scroll to the bottom of the course information page and choose the Enroll Now link.
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