ABSTRACT OF THE WEEK

Journal of veterinary internal medicine/ American College of Veterinary Internal Medicine
Volume 30 | Issue 6 (2016 Nov-Dec)

Subclinical Bacteriuria in Older Cats and its Association with Survival.

J Vet Intern Med. 2016 Nov-Dec;30(6):1824-1829.

J D White¹, N J Cave², A Grinberg³, D G Thomas⁴, C Heuer⁵

¹ Massey University Veterinary Teaching Hospital, Palmerston North, New Zealand.; ² Institute of Veterinary, Animal & Biomedical Sciences, Palmerston North, New Zealand.; ³ Institute of Veterinary, Animal & Biomedical Sciences, Palmerston North, New Zealand.; ⁴ Institute of Veterinary, Animal & Biomedical Sciences, Palmerston North, New Zealand.; ⁵ EpiCentre, Massey University, Palmerston North, New Zealand.

Abstract

BACKGROUND:Bacterial urinary tract infections are uncommon in cats in general but the prevalence increases to 29% in older cats with comorbidities (Veterinary Clinical Pathology 2008, 37, 317; Journal of Feline Medicine & Surgery 2007, 9, 124; Veterinary Microbiology 2009, 136, 130). Frequently, the infections are subclinical. The clinical relevance of subclinical bacteriuria (SB) is uncertain, and the optimal treatment requires clarification.

OBJECTIVE:Prospective, observational study to: (i) identify the prevalence and incidence count of SB in older (≥7 years), nonazotemic cats, (ii) evaluate specific risk factors for SB, and (iii) investigate the potential relationship between untreated SB and survival.

ANIMALS:Sixty-seven, nonazotemic cats were tested on 5 occasions over 3 years.

METHODS:Urine samples were obtained by cystocentesis for quantitative urine culture and blood samples for measurement of serum creatinine concentration. Episodes of SB were not treated. Serum creatinine concentration, body weight, urine specific gravity, sex, and age were evaluated as potential risk factors for a positive urine culture. The association between urine culture results and survival was evaluated with Cox's proportional hazard model.

RESULTS:A total of 256 urine samples was obtained. The prevalence of SB varied between 10 and 13%, and incident infections were uncommon. Female cats were 21 times more likely to have a positive urine culture than were male cats (odds ratio [OR], 21.2; confidence interval [CI], 4.1-110; P = .00028). Subclinical bacteriuria was not significantly associated with survival.

CONCLUSION AND CLINICAL IMPORTANCE:Subclinical bacteriuria is common in nonazotemic, older cats. Although antimicrobial treatment was withheld, the presence of SB was not adversely associated with survival.

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Cites J Am Vet Med Assoc. 1991 Jul 15;199(2):211-6
Cites Br Med J. 1969 Mar 29;1(5647):804-6
Cites Ann Intern Med. 1994 May 15;120(10):827-33
Cites J Am Vet Med Assoc. 1997 Jan 1;210(1):46-50
Cites J Vet Intern Med. 1999 Nov-Dec;13(6):557-60
Cites N Engl J Med. 2000 Oct 5;343(14):992-7
Cites J Am Vet Med Assoc. 2001 May 1;218(9):1429-35
Cites N Engl J Med. 2002 Nov 14;347(20):1576-83
Cites J Vet Intern Med. 2004 May-Jun;18(3):301-6
Cites Crit Care. 2005 Feb;9(1):112-8
Cites J Am Vet Med Assoc. 2005 Jul 15;227(2):239-43
Cites J Vet Intern Med. 2006 Mar-Apr;20(2):245-9
Cites Int J Antimicrob Agents. 2006 Aug;28 Suppl 1:S42-8
Cites J Vet Intern Med. 2006 Jul-Aug;20(4):850-5
Cites J Feline Med Surg. 2007 Apr;9(2):124-32
Cites Arch Intern Med. 2006 Nov 13;166(20):2222-7
Cites J Infect Dis. 2008 Jan 15;197(2):218-24
Cites Ann Intern Med. 2008 Jul 1;149(1):43-7
Cites Vet Clin Pathol. 2008 Sep;37(3):317-22
Cites Vet Microbiol. 2009 Apr 14;136(1-2):130-4
Cites Clin Geriatr Med. 2009 Aug;25(3):423-36
Cites J Vet Intern Med. 2009 Nov-Dec;23(6):1175-83
Cites J Feline Med Surg. 2013 Jun;15(6):459-65
Cites J Feline Med Surg. 2015 Feb;17(2):125-33

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