DIAG301-0714: Oncology and Tumor Pathology II
In some of the course Real Time Sessions the lecture will be predominantly audio
while in others the lecture will be predominantly text.

Enrollment is closed.

INSTRUCTOR(S): Dr. med. vet. habil. Matti Kiupel, PhD, DACVP
Craig A. Clifford, DVM, MS, DACVIM (Oncology)
Phil Bergman, DVM, MS, PhD, DACVIM (Oncology)
Rebecca Smedley, DVM, MS, DACVP

COURSE OPEN: July 8-August 29, 2014
REAL TIME SESSIONS (RTS): Tuesdays, July 15, 22, 29, August 5, 12, and 19, 2014; 8:00-10:00 pm ET (US)
Course RTS Times in Your Area: World Clock Converter

Practice Sessions: In order to prepare you for a successful experience in your CE course, we request you attend a Practice Session prior to the first Real Time Session. Please arrive promptly at the start time; each Practice Session is up to 1 hour in length. For more information, please visit the CE Practice Area.

*The instructors for this course will be using audio which will require you to have a headset or speakers to listen. If you have any concerns regarding your computer's audio capabilities, please be sure to attend one of the Practice Sessions.

Level and Prerequisites: This advanced course will be open to veterinarians actively interested in actively interested in canine and feline oncology and tumor pathology. Participants should have a strong interest and/or experience in oncology.
VIN CE Course: Open to veterinarians. This course is RACE approved for veterinarians. The Veterinary Information Network (VIN) is RACE Provider #22.

Course Description:
This is the second of two modules on oncology and tumor pathology. This course can be taken independently of the first module (DIAG300-0414: Oncology and Tumor Pathology I).

This course will familiarize participants with the current state of tumor diagnosis and prognosis as well as therapeutic interventions. The first real time session will provide an overview of principles and advances in surgical pathology and an introduction to clinical oncology, and is a review of the basic information covered during the first real time session for DIAG300-0414: Oncology and Tumor Pathology I. This course will cover canine/feline histiocytic diseases, canine/feline soft tissue sarcomas, canine/feline osteosarcoma, canine melanomas, and canine/feline mammary tumors.

The pathology segments will discuss the classical histologic criteria to diagnosis and prognosticate neoplastic diseases including the newest grading systems. Furthermore, the participants will be introduced to modern molecular pathology tests that further our prognostic capabilities and help determine therapeutic protocols, such as immunohistochemical tumor diagnostic and prognostic panels.

From the clinical oncology perspective, this course will familiarize the participants with the basic surgical aspects of veterinary oncology including: routine staging of patients, proper aspirate and biopsy techniques as well as the preferred approach for a definitive surgery when appropriate. The remaining lectures are designed to highlight the etiology (with an emphasis on the latest research regarding genetic aspects of the specific tumor type) and typical signalment, clinical signs, staging, diagnosis, therapy and prognosis for specific histologies. A special emphasis will be provided on the latest research for each cancer type regarding the use of novel targeted therapies when appropriate.

This course consists of six (6) 2-hour Real Time Session, supplemental library materials, interactive message board discussions, and a mandatory end-of-course test. Successful completion (scoring 80% or better) on the end-of-course test is required to earn a certificate of completion for the course.

Upon completion of this course, the participant should be able to

• submit high quality tumor biopsy samples for microscopic evaluation, margin evaluation, and advanced molecular testing from various organs.
• recognize the current histologic grading schemes for the neoplastic entities discussed.
• understand and integrate advanced molecular testing to determine tumor prognosis and for therapeutic decision making.
• demonstrate an understanding of the indications for and differences between incisional and excisional biopsies.
• demonstrate an understanding of the difference between staging and grading while also gaining an appreciation for general staging recommendations for the various cancers covered in the course.
• recognize the etiology (with an emphasis on the latest research regarding genetic aspects of the specific tumor type) and typical signalment, clinical signs, staging, diagnosis, therapy and prognosis for:
  • Histiocytic sarcoma
  • Soft tissue sarcoma
  • Osteosarcoma
  • Melanoma
  • Mammary tumors
• demonstrate an appreciation for the latest research for each cancer type regarding the use of novel targeted therapies when appropriate.

Course Materials: Course materials will be available in the course library prior to each Real Time Session.

Required Textbook(s): There is no required textbook for this course.

About the Instructors:
Dr. Matti Kiupel is a board certified veterinary pathologist with extensive experience in tumor pathology and molecular pathology. He is Professor at Michigan State University and Section Chief of Anatomic Pathology at the Diagnostic Center for Population and Animal Health. Dr. Kiupel is an internationally renowned speaker and has won numerous lecturer awards and authored more than 200 peer-reviewed scientific publications. Together with Dr. Smedley he is editor of the WSAVA online atlas of Tumor Classification of Domestic Animals.

Dr. Phil Bergman is a medical oncologist and the Director of Clinical Studies for VCA at the Katonah-Bedford Veterinary Center, a 24/7 Specialty/ER center in Westchester County, NY. He is the principal veterinary investigator for the recently fully licensed canine melanoma vaccine (Oncept) available from Merial. Dr. Bergman is an adjunct faculty member of the Memorial Sloan-Kettering Cancer Center and will continue/expand his cancer vaccine program within the VCA Antech network.

Dr. Craig Clifford is a medical oncologist and the Director of Clinical Studies for Hope Veterinary Specialists in Malvern PA. Dr. Clifford is a well renowned oncologist who has authored/co-authored over 30 papers and book chapters. He was responsible for the creation of resident review sponsored by the Veterinary Cancer Society and the Northeast Veterinary Co-operative Oncology Group. He is a frequent lecturer at major veterinary meetings in the USA and internationally. Dr. Clifford is currently serving on the VCS executive board, the ACVIM Exam Rating Committee, the Residency Training and Credentials Committee and is the Co-chair of the Standards of Excellence in Residency Education Task Force.

Rebecca Smedley is a board certified veterinary pathologist with extensive experience in tumor pathology and molecular pathology. She is an Academic Specialist at the Diagnostic Center for Population and Animal Health at Michigan State University. Dr. Smedley is first and collaborating author on a large number of peer-reviewed scientific publications in the field of tumor pathology and has been an invited speaker on these topics to national and international scientific conferences. Together with Dr. Kiupel she is editor of the WSAVA online atlas of Tumor Classification of Domestic Animals.

Course Outline:
Week 1 (Real Time Session July 15, 2014): Tumor Pathology and Clinical Oncology Basics
Instructor(s): Dr. med. vet. habil. Matti Kiupel, PhD, DACVP
Craig A. Clifford, DVM, MS, DACVIM (Oncology)
Phil Bergman, DVM, MS, PhD, Diplomate ACVIM (Oncology)
Rebecca Smedley, DVM, MS, DACVP
Content:

• Overview of tumor growth
• Advantages and disadvantages of cytology versus histology
• Proper collection and submission of a biopsy
• Understanding trimming methods and margin evaluation
• Reading a pathology report
• Why worry about cancer in pets?
• The etiology of cancer
• The hallmarks of cancer
• Basics of tumor biology and metastasis
• Review of paraneoplastic syndromes

Week 2 (Real Time Session July 22, 2014): Canine/Feline Histiocytic Diseases
Instructor(s): Dr. med. vet. habil. Matti Kiupel, PhD, DACVP
Craig A. Clifford, DVM, MS, DACVIM (Oncology)
Rebecca Smedley, DVM, MS, DACVP
Content:

• Overview of the various types of histiocytic diseases in the dog including:
  • Reactive cutaneous histiocytosis
  • Reactive systemic histiocytosis
  • Cutaneous histiocytoma
  • Langerhans histiocytosis
  • histiocytic sarcoma including:
    • periarticular histiocytic sarcoma and hemophagocytic histiocytic sarcoma;
    • Morphologic and immunohistochemical differentiation between these different entities.
• Overview of feline progressive histiocytosis
• Brief review of the histiocytic disease lineage
• Review of the staging for canine and feline histiocytic sarcoma
• Indications and options for adjuvant treatments in canine histiocytic sarcoma
• Brief discussion regarding diagnosis and treatment of histiocytic variants including feline progressive histiocytosis and hemophagocytic histiocytic sarcoma.

Week 3 (Real Time Session July 29, 2014): Canine/Feline Mammary Tumors
Instructor(s): Dr. med. vet. habil. Matti Kiupel, PhD, DACVP
Craig A. Clifford, DVM, MS, DACVIM (Oncology)
Phil Bergman, DVM, MS, PhD, Diplomate ACVIM (Oncology)
Rebecca Smedley, DVM, MS, DACVP
Content:

• Morphologic diagnosis of canine/feline mammary tumors
• Differentiation between benign and malignant tumors
• Discussion of the various morphologic subtypes of these tumors
• Grading of canine and feline mammary tumors
• Immunohistochemical evaluation of canine/feline mammary tumors
• Timing of OHE and risk of development of mammary gland tumors (MGT) in dogs and cats
• Staging recommendations for canine and feline MGT
• Differences in Sx recommendations for MGT's in dogs and cats
• Prognostic factors in canine and feline MGT's and when to use adjuvant therapies

Week 4 (Real Time Session August 5, 2014): Canine/Feline Osteosarcoma
Instructor(s): Dr. med. vet. habil. Matti Kiupel, PhD, DACVP
Phil Bergman, DVM, MS, PhD, Diplomate ACVIM (Oncology)
Rebecca Smedley, DVM, MS, DACVP
Content:

• Importance of obtaining a diagnostic bone biopsy specimen and recommendations on how to achieve this
• Importance of concurrent evaluation of radiographic findings
• Morphologic diagnosis of various subtypes of osteosarcoma
• Discussion of differential diagnoses
• Staging recommendations for canine and feline osteosarcoma
• Surgical treatment options and expectations of outcome in canine and feline OSA
• Palliative treatment options for OSA
• Indications and options for adjuvant treatments in canine and feline OSA

Week 5 (Real Time Session August 12, 2014): Canine Melanoma
Instructor(s): Dr. med. vet. habil. Matti Kiupel, PhD, DACVP
Phil Bergman, DVM, MS, PhD, Diplomate ACVIM (Oncology)
Rebecca Smedley, DVM, MS, DACVP
Content:

• Morphologic and immunohistochemical diagnosis of canine melanocytic neoplasms
• Differences between cutaneous, oral, mucocutaneous, and digit melanocytic neoplasms
• Prognostic markers for canine melanocytic neoplasms
• Staging recommendations for canine and feline melanoma
• Surgical treatment options and expectations of outcome in canine and feline melanoma
• Use of radiation for the treatment of melanoma
• Adjuvant immunotherapy treatment of malignant melanoma

Week 6 (Real Time Session August 19, 2014): Canine/Feline Soft Tissue Sarcoma
Instructor(s): Dr. med. vet. habil. Matti Kiupel, PhD, DACVP
Craig A. Clifford, DVM, MS, DACVIM (Oncology)
Rebecca Smedley, DVM, MS, DACVP
Content:

• Incisional versus excisional biopsy of canine/feline soft tissue sarcomas
• Morphologic and immunohistochemical diagnosis of canine/feline soft tissue sarcomas
• Grading of canine soft tissue sarcomas
• Discussion of the specific histologies included under the umbrella terms "soft tissue sarcoma"
• Discussion of injection site sarcomas vs. non injection site sarcomas
• Review of staging recommendations
• Surgical and radiation therapy treatment options and expected outcomes in canine and feline soft tissue sarcomas
• Review of metronomic therapy for incompletely excised soft tissue sarcomas in the canine
• Palliative treatment options for canine and feline soft tissue sarcoma

CE CREDITS: 12

Tuition: Member $252 ($227 early bird special if enrolled by June 24, 2014)
Non-Member $374 ($337 early bird special if enrolled by June 24, 2014)

*To ensure participants are ready and prepared for classes, enrollment will close at 5 pm ET July 8, 2014 or when the maximum number of participants is reached.
*For more information on how online CE works, see the Participant Resource Center.

TO ENROLL:
Enrollment is closed.

1. Enrollment qualifications: VIN CE courses are open to VIN member and non-member veterinarians. Veterinarians enrolling in a VSPN CE course must be a VIN member. Veterinary support staff must be a VSPN member to enroll in a VSPN CE or a VIN CE course open to VSPN member enrollment.
2. Each enrollee must be able to receive emails from @vspn.org and @vin.com addresses. Email is our major form of communication with participants; personal emails are highly recommended rather than clinic/hospital email addresses.
3. Each person is individually responsible for his/her own registration. To ensure that all information received is secure and correct, please do not enroll for a course on behalf of another individual.
4. For further assistance call 1-800-700-INFO (4636) or email (VIN CE) CEonVIN@vin.com or (VSPN CE) VSPNCE@vspn.org. Please include the course title, your full name, and contact information in your correspondence.

*Note: "This course is approved for 12 continuing education credits in jurisdictions which recognize AAVSB RACE approval; however participants should be aware that some boards have limitations on the number of hours accepted in certain categories and/or restrictions on certain methods of delivery of continuing education." Call VSPN/VIN CE at 1-800-700-4636 for further information. (Attendees are encouraged to check with their licensing jurisdiction(s) for information regarding recognition by their board).

Course withdrawal and refund policy: A complete refund of the paid course price will be issued when your withdrawal request is received prior to the listed start date of the course. If you wish to withdraw after the start date please contact the VIN/VSPN office 1-800-700-INFO (4636) to discuss eligibility for a pro-rated refund.
* Note: To ensure rapid handling of your request for withdrawal, we recommend that you call the VIN/VSPN office at 1-800-700-INFO (4636).

*For more information on VIN's upcoming CE courses, check the VIN Course Catalog.

The CE team:

Katherine James, DVM, PhD, DACVIM (SAIM)
VIN Education Coordinator

VIN CE Services: CEonVIN@vin.com
800-846-0028 or 530-756-4881; ext. 797
or direct line to VIN/VSPN from the United Kingdom: 01452226154

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